50-172-6018
beta Tubulin Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech
Manufacturer: Proteintech Group Inc
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 50-172-6018-Each-of-1 | In Stock | ₹ 39,071.00 |
50-172-6018 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 39,071.00
GST (18%): ₹ 7,032.78
Total Price: ₹ 46,103.78
Antigen
beta Tubulin
Classification
Polyclonal
Conjugate
Unconjugated
Gene
TUBB3
Gene Alias
beta tubulin, tbb5, TUBB
Host Species
Rabbit
Purification Method
Antigen Affinity Chromatography
Regulatory Status
RUO
Gene ID (Entrez)
10381, 22152, 246118
Content And Storage
-20°C
Form
Liquid
Applications
Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Immunoprecipitation
Concentration
0.26 mg/mL
Formulation
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
Gene Accession No.
Q13509, Q4QRB4, Q9ERD7
Gene Symbols
TUBB3
Immunogen
beta Tubulin Fusion Protein Ag0136
Quantity
150 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Beta tubulins are one of two core protein families (alpha and beta tubulins) that heterodimerize and assemble to form microtubules
- Beta-III tubulin is primarily expressed in neurons and may be involved in neurogenesis, axon guidance and maintece
- Mutations in the beta tubulin gene are the cause of congenital fibrosis of the extraocular muscles type 3
- Beta-III tubulin was also detected in Sertoli cells of the testis and transiently in non-neuronal embryonic tissues
- Glutamate residues at the C-terminus of beta III tubulin can be glutamylated
- The precise function of such modifications is unclear
- Tubulin is phosphorylated on Ser-172 by CDK1 during cell cycle progression
- Ser-172 phosphorylation inhibits tubulin incorporation into microtubules
- Microtubules, the major cytoskeletal elements found in all eukaryotic cells, consist of Tubulin, which is a dimer of two 55 kDa subunits: alpha and Beta
- Microtubules play key roles in chromosome segregation in mitosis, intracellular transport, ciliary and flagellar bending, and structural support of the cytoskeleton
- Because beta-tubulin is ubiquitously expressed in all eukaryotic cells, it is frequently used as a loading control for assays involving protein detection, such as Western blotting.