50-172-6123
CDC37 Rabbit anti-Human, Mouse, Non-human primate, Rat, Polyclonal, Proteintech
Manufacturer: Proteintech Group Inc
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 50-172-6123-Each-of-1 | In Stock | ₹ 44,150.23 |
50-172-6123 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 44,150.23
GST (18%): ₹ 7,947.041
Total Price: ₹ 52,097.271
Antigen
CDC37
Classification
Polyclonal
Conjugate
Unconjugated
Gene
CDC37
Gene Alias
CDC37, CDC37A, Hsp90 co chaperone Cdc37, P50CDC37
Host Species
Rabbit
Purification Method
Antigen Affinity Chromatography
Regulatory Status
RUO
Gene ID (Entrez)
11140, 114562, 12539
Content And Storage
-20°C
Form
Liquid
Applications
Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Immunoprecipitation
Concentration
0.2 mg/mL
Formulation
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
Gene Accession No.
Q16543, Q61081, Q63692
Gene Symbols
Cdc37
Immunogen
CDC37 Fusion Protein Ag0267
Quantity
150 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Non-human Primate, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- In S
- cerevisiae, Cdc37 has been shown to be an important regulator of cell division cycle through its action on cyclin-dependent kinases (CDK′s)
- Cdc37 has also been associated with signaling pathways and kinases unrelated to cell cycle control, including v-Src, casein kinase II, MPS1 kinase and the sevenless receptor tyrosine kinase
- Interestingly, HSP90 has also been shown to be associated with many of the same cellular targets as Cdc37
- It has now been shown that Cdc37 is the same protein previously described as p50 which has been found to be associated with many of the same proteins as HSP90
- Among others, Cdc37/p50 has been found complexed with Src-family kinases (Fyn, Yes, Fes, Lck and Fgr), Raf and pp60v-src
- More recently, Cdc37 has been shown to be a chaperone independently and in concert with HSP90
- In fact, Cdc37 is necessary for the binding of HSP90 to Cdk4.