50-172-6351
GAPDH Rabbit anti-Human, Mouse, Plant, Porcine, Rat, Polyclonal, Proteintech
Manufacturer: Proteintech Group Inc
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 50-172-6351-Each-of-1 | In Stock | ₹ 39,071.00 |
50-172-6351 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 39,071.00
GST (18%): ₹ 7,032.78
Total Price: ₹ 46,103.78
Antigen
GAPDH
Classification
Polyclonal
Conjugate
Unconjugated
Gene
GAPDH
Gene Alias
G3PD, GAPD, GAPDH, OK/SW cl.12
Host Species
Rabbit
Purification Method
Antigen Affinity Chromatography
Regulatory Status
RUO
Gene ID (Entrez)
14433, 24383, 2597, 396823
Content And Storage
-20°C
Form
Liquid
Applications
Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Immunoprecipitation
Concentration
0.33 mg/mL
Formulation
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
Gene Accession No.
P00355, P04406, P04797, P16858
Gene Symbols
GAPDH
Immunogen
GAPDH Fusion Protein Ag0766
Quantity
150 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Plant, Porcine, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- This antibody is raised against full length GAPDH of human origin
- It can recognize the 36 kDa GAPDH protein in most cells/tissues
- In addition, a band below 36 kDa can always be detected as the isoform or spliced product of GAPDH
- Please note that some p GAPDH (Glyceraldehyde-3-phosphate dehydrogenase) is a catalytic enzyme commonly known to be involved in glycolysis
- GAPDH exists as a tetramer of identical 37- kDa subunits and catalyzes the reversible reduction of 1,3-bisphosphoglycerate to glyceraldehyde 3-phosphophate in the presence of NADPH
- Apart from playing a key role in glycolysis, GAPDH is ubiquitously expressed and displays other activities unrelated to its glycolytic function
- GAPDH is reported to be involved in the processes of DNA replication, DNA repair, nuclear RNA export, membrane fusion and microtubule bundling
- Studies provide evidence of GAPDH playing an essential part in gene expression observed in apoptosis and as part of the cellular phenotype of age-related neurodegenerative diseases
- Further, GAPDH is involved in other cellular processes ranging from membrane fusion, and neuronal apoptosis in cancer
- GAPDH is reported to bind to a variety of other proteins, including the amyloid precursor protein, mutations in which cause some forms of Alzheimer′s disease (AD), and the polyglutamine tracts of Huntingtin, the protein product aberrant forms of which are causative of Huntington′s disease
- Associations between GAPDH, actin and tubulin have also be reported
- Since GAPDH is expressed at high levels in most tissues, it is useful as protein loading control in Western Blot analysis.