50-173-0094
GEMIN8 Rabbit anti-Human, Polyclonal, Proteintech
Manufacturer: Proteintech Group Inc
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 50-173-0094-Each-of-1 | In Stock | ₹ 44,150.23 |
50-173-0094 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 44,150.23
GST (18%): ₹ 7,947.041
Total Price: ₹ 52,097.271
Antigen
GEMIN8
Classification
Polyclonal
Conjugate
Unconjugated
Gene
GEMIN8
Gene Alias
FAM51A1, Gem associated protein 8, Gemin 8, GEMIN8, Protein FAM51A1
Host Species
Rabbit
Purification Method
Antigen Affinity Chromatography
Regulatory Status
RUO
Gene ID (Entrez)
54960
Content And Storage
-20°C
Form
Liquid
Applications
Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Concentration
0.27 mg/mL
Formulation
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No.
Q9NWZ8
Gene Symbols
GEMIN8
Immunogen
GEMIN8 Fusion Protein Ag6774
Quantity
150 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Related Products
Description
- This antibody recognize GEMIN8 (28-32 kDa) only
- The SMN complex plays a catalyst role in the assembly of small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome
- Thereby, plays an important role in the splicing of cellular pre-mRNAs
- Most spliceosomal snRNPs contain a common set of Sm proteins SNRPB, SNRPD1, SNRPD2, SNRPD3, SNRPE, SNRPF and SNRPG that assemble in a heptameric protein ring on the Sm site of the small nuclear RNA to form the core snRNP
- In the cytosol, the Sm proteins SNRPD1, SNRPD2, SNRPE, SNRPF and SNRPG are trapped in an inactive 6S pICln-Sm complex by the chaperone CLNS1A that controls the assembly of the core snRNP
- Dissociation by the SMN complex of CLNS1A from the trapped Sm proteins and their transfer to an SMN-Sm complex triggers the assembly of core snRNPs and their transport to the nucleus.