50-173-7042

GSTA1 Mouse anti-Human, Mouse, Porcine, Rat, Clone: 1E1F4, Proteintech

Manufacturer: Proteintech Group Inc

Select a Size

Pack Size SKU Availability Price
Each of 1 50-173-7042-Each-of-1 In Stock ₹ 44,150.23

50-173-7042 - Each of 1

₹ 44,150.23

In Stock

Quantity

1

Base Price: ₹ 44,150.23

GST (18%): ₹ 7,947.041

Total Price: ₹ 52,097.271

Antigen

GSTA1

Classification

Monoclonal

Concentration

1 mg/mL

Formulation

PBS with 50% glycerol and 0.1% sodium azide; pH 7.3

Gene Accession No.

P00502, P08263, P13745, P51781

Gene Symbols

GSTA1

Immunogen

GSTA1 Fusion Protein Ag6084

Quantity

150 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Porcine, Rat

Product Type

Antibody

Isotype

IgG1

Applications

Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Clone

1E1F4

Conjugate

Unconjugated

Gene

GSTA1

Gene Alias

Glutathione S transferase A1, GST class alpha member 1, GST epsilon, GST HA subunit 1, GST2, GSTA1, GSTA1 1, GTH1

Host Species

Mouse

Purification Method

Protein G

Regulatory Status

RUO

Gene ID (Entrez)

14857, 24421, 2938, 397682

Content And Storage

-20°C

Form

Liquid

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Description

  • Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families
  • These enzymes function in the detoxification of electrophilic compounds, including carcinogens, therapeutic drugs, environmental toxins and products of oxidative stress, by conjugation with glutathione
  • The genes encoding these enzymes are known to be highly polymorphic
  • These genetic variations can change an individuals susceptibility to carcinogens and toxins as well as affect the toxicity and efficacy of some drugs
  • At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta
  • This gene encodes a glutathione S-tranferase belonging to the alpha class
  • The alpha class genes, located in a cluster mapped to chromosome 6, are the most abundantly expressed glutathione S-transferases in liver
  • In addition to metabolizing bilirubin and certain anti-cancer drugs in the liver, the alpha class of these enzymes exhibit glutathione peroxidase activity thereby protecting the cells from reactive oxygen species and the products of peroxidation.