50-177-00
VAP-1 Monoclonal Antibody (TK8-14), eBioscience™, Invitrogen™
Manufacturer: Invitrogen
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 50-177-00-Each-of-1 | In Stock | ₹ 31,150.00 |
50-177-00 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 31,150.00
GST (18%): ₹ 5,607.00
Total Price: ₹ 36,757.00
Antigen
VAP-1
Classification
Monoclonal
Concentration
1 mg/mL
Formulation
PBS with no preservative; pH 7.2-7.4
Gene Accession No.
Q16853
Gene Symbols
AOC3
Immunogen
Rec. Human VAP-1
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG2a
Applications
ELISA, Flow Cytometry, Immunohistochemistry, Western Blot
Clone
TK8-14
Conjugate
Unconjugated
Gene
AOC3
Gene Alias
amine oxidase, copper containing 3; amine oxidase, copper containing 3 (vascular adhesion protein 1); Aoc3; Copper amine oxidase; HPAO; Membrane primary amine oxidase; placenta copper monamine oxidase; semicarbazide-sensitive amine oxidase; SSAO; VAP1; VAP-1; Vascular adhesion protein 1; VP97
Host Species
Mouse
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
8639
Content And Storage
-20°C
Form
Liquid
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Description
- Description: VAP-1 (TK8-14) is a mouse monoclonal antibody raised against affinity purifiedVAP-1 from tonsil stroma of human origin
- Lymphocyte binding to vascular endothelium is a prerequisite for the move-ment of immune cells from the blood into lymphoid tissues and into sites ofinflammation
- Under inflammatory conditions, cell surface expression ofVAP-1 (vascular adhesion protein-1) which is an endothelial sialoglycoprotein,is induced
- VAP-1 is a type II transmembrane protein of 84.6 kDa with a singletransmembrane domain and N and O-glycosylation sites in the extracellulardomain
- In vivo, VAP-1 exists predominantly as a 180 kDa homodimer andfunctions both as an enzyme (monoamine oxidase) and an adhesion moleculefor lymphocytes
- Applications Tested: ELISA, Flow Cytometry, Immunofluorescence, Western Blotting
- Copper amine oxidases catalyze the oxidative conversion of amines to aldehydes in the presence of copper and quinone cofactor
- The product is a major protein on the adipocyte plasma membrane
- It has adhesive properties and also has functional monoamine oxidase activity
- A pseudogene for this gene has been discribed and is located approximately 9-kb downstream.