50-194-3789

ThyroglobulinMouse anti-Canine, Human, Mouse, Rat, Clone: 2H11, Rockland™

Manufacturer: Rockland Immunochemicals

Select a Size

Pack Size SKU Availability Price
Each of 1 50-194-3789-Each-of-1 In Stock ₹ 53,980.28

50-194-3789 - Each of 1

₹ 53,980.28

In Stock

Quantity

1

Base Price: ₹ 53,980.28

GST (18%): ₹ 9,716.45

Total Price: ₹ 63,696.73

Antigen

Thyroglobulin

Classification

Monoclonal

Concentration

1.6 mg/mL

Formulation

0.02M potassium phosphate with 0.5M NaCl and 0.01% sodium azide; pH 7.2

Gene Accession No.

O08710, P01266, P06882

Gene Symbols

TG

Immunogen

This protein A purified monoclonal antibody was produced by repeated immunizations with human thyroglobulin protein.

Regulatory Status

RUO

Gene ID (Entrez)

21819, 24826, 482047, 7038

Content And Storage

-20°C, Avoid Freeze/Thaw Cycles

Form

Liquid

Applications

ELISA, Immunohistochemistry, Immunoprecipitation, Western Blot

Clone

2H11

Conjugate

Unconjugated

Gene

TG

Gene Alias

AITD3; cog; Colloid; congenital goiter; Tg; Tgn; Thyroglobulin

Host Species

Mouse

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Canine, Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG1

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Description

  • Store vial at -20°C prior to opening
  • Aliquot contents and freeze at -20°C or below for extended storage
  • Avoid cycles of freezing and thawing
  • Centrifuge product if not completely clear after standing at room temperature
  • This product is stable for several weeks at 4°C as an undiluted liquid
  • Dilute only prior to immediate use
  • Reacts specifically with thyroglobulin in human tissues
  • The antibody recognizes a 330-kDa band corresponding to thyroglobulin
  • Cross reactivity with thyroglobulin from mouse, rat and dog will occur
  • Cross reactivity with thyroglobulin from other sources has not been determined
  • The human thyroglobulin (hTg) is a high molecular weight glycoprotein (605 kDa) found in the thyroid follicular cells
  • It plays a central role in the uptake, incorporation, and regulated biosynthesis of thyroid hormones, T4 and T3
  • Thyroid disorders are, in large part, due to autoimmune origin, and anti-thyroglobulin autoantibodies were the first factor to be discovered
  • Anti-hTG is found in all thyroid autoimmune diseases (Hashimoto thyroiditis, Graves diseases), with the highest level observed in Hashimoto thyroiditis
  • Anti-hTG is also characteristic of thyroid cancer, and its determination can be used for the follow up of cancer patients.