50-199-2759
5-Methylcytosine (5-mC) Mouse anti-Human, Clone: 33D3, Active Motif™
Manufacturer: Active Motif
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 50-199-2759-Each-of-1 | In Stock | ₹ 27,768.00 |
50-199-2759 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 27,768.00
GST (18%): ₹ 4,998.24
Total Price: ₹ 32,766.24
Antigen
5-Methylcytosine (5-mC)
Classification
Monoclonal
Concentration
1 mg/mL
Formulation
10mM phosphate with 0.15M NaCl and 0.01% thimerosal; pH 7.5
Host Species
Mouse
Purification Method
Protein A
Regulatory Status
RUO
Target Species
Human
Product Type
Antibody
Isotype
IgG
Applications
Immunohistochemistry, Immunoprecipitation, Western Blot
Clone
33D3
Conjugate
Unconjugated
Gene Alias
5mc; 5-mC; 5-meC; 5-Methyl-cytosine; C5H7NO3
Immunogen
Clone 33D3 recognizes the modified base 5-methylcytidine found in plant and vertebrate DNA.
Quantity
50 μg
Primary or Secondary
Primary
Content And Storage
-20°C, Avoid Freeze/Thaw Cycles
Form
Liquid
Related Products
Description
- Methylation of DNA cytosine bases plays important roles in the regulation of gene transcription
- It has been estimated that 60 to 90% of the cytosines in CpG dinucleotides are methylated
- An increase in methyl-CpG correlates with transcriptional silencing for the whole chromosome especially in developmentally regulated genes
- Methylation is believed to lead to transcriptional silencing by multiple mechanisms including alteration of transcription factor binding to promoters and alteration in chromatin structure.