50-194-3852

Phospho-DNA PKcs (Thr2609)Rabbit anti-Chimpanzee, Human, Polyclonal, Rockland™

Manufacturer: Rockland Immunochemicals

Select a Size

Pack Size SKU Availability Price
Each of 1 50-194-3852-Each-of-1 In Stock ₹ 52,930.08

50-194-3852 - Each of 1

₹ 52,930.08

In Stock

Quantity

1

Base Price: ₹ 52,930.08

GST (18%): ₹ 9,527.414

Total Price: ₹ 62,457.494

Antigen

Phospho-DNA PKcs (Thr2609)

Classification

Polyclonal

Conjugate

Unconjugated

Gene

PRKDC

Gene Alias

AI326420; AU019811; DNA-dependent protein kinase catalytic subunit; DNAPDcs; DNAPK; DNA-PK catalytic subunit; DNA-PKcs; DNPK1; DOXNPH; doxorubicin nephropathy; dxnph; hyper-radiosensitivity of murine scid mutation, complementing 1; HYRC; HYRC1; I79_017613; IMD26; p350; p460; PRKDC; protein kinase, DNA activated, catalytic polypeptide; protein kinase, DNA-activated, catalytic polypeptide; scid; severe combined immunodeficiency; slip; Xrcc7

Host Species

Rabbit

Regulatory Status

RUO

Gene ID (Entrez)

464165, 5591

Content And Storage

-20°C, Avoid Freeze/Thaw Cycles

Form

Liquid

Applications

ELISA, Immunoprecipitation, Western Blot

Concentration

1 mg/mL

Formulation

0.02M potassium phosphate with 0.15M NaCl and 0.01% sodium azide; pH 7.2

Gene Accession No.

P78527

Gene Symbols

PRKDC

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Chimpanzee, Human

Product Type

Antibody

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Description

  • Store vial at -20°C prior to opening
  • Aliquot contents and freeze at -20°C or below for extended storage
  • Avoid cycles of freezing and thawing
  • Centrifuge product if not completely clear after standing at room temperature
  • This product is stable for several weeks at 4°C as an undiluted liquid
  • Dilute only prior to immediate use
  • DNA PKcs pT2609 antibody is directed against the phosphorylated form of human DNA PKcs at the pT2609 residue
  • This phospho-specific polyclonal antibody reacts with phosphorylated pT2609 of human DNA PKcs
  • Reactivity with non-phosphorylated human DNA PKcs is minimal
  • A BLAST analysis was used to suggest reactivity with this protein from human and chimpanzee based on 100% homology for the immunogen sequence
  • However, cross-reactivity is expected with mouse, rat, dog, chicken and horse DNA PKcs based on a high degree of homology to the immunogen sequence
  • Cross-reactivity with DNA PKcs homologues from other sources has not been determined
  • This gene encodes a component of the mediator complex, a transcriptional coactivator complex thought to be required for the expression of almost all genes
  • The mediator complex is recruited by transcriptional activators or nuclear receptors to induce gene expression, possibly by interacting with RNA polymerase II and promoting the formation of a transcriptional pre-initiation complex
  • Multiple transcript variants encoding different isoforms have been found for this gene.