Phospho-CSF1R (Tyr723) Rabbit anti-Human, Polyclonal, Bioss
Manufacturer: Bioss
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 50-198-5126-Each-of-1 | In Stock | ₹ 38,381.25 |
50-198-5126 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 38,381.25
GST (18%): ₹ 6,908.625
Total Price: ₹ 45,289.875
Antigen
Phospho-CSF1R (Tyr723)
Classification
Polyclonal
Conjugate
Unconjugated
Gene
Csf1r
Gene Alias
AI323359; CD115; CD115 antigen; C-FMS; colony stimulating factor 1 receptor; CSF-1 receptor; CSF1R; CSF-1R; CSF-1-R; Csfmr; CSFR; EC 2.7.10.1; FIM2; Fim-2; Fms; fms proto-oncogene; HDLS; kinase CSFR; macrophage colony stimulating factor I receptor; Macrophage colony-stimulating factor 1 receptor; McDonough feline sarcoma viral (v-fms) oncogene homolog; M-CSFR; M-CSF-R; mrfms; OTTHUMP00000224093; PDGFRB; Proto-oncogene c-Fms; proto-oncogene fms
Host Species
Rabbit
Purification Method
Protein A
Regulatory Status
RUO
Gene ID (Entrez)
1436
Content And Storage
-20°C
Form
Liquid
Applications
Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Concentration
1 μg/mL
Formulation
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene Accession No.
P07333
Gene Symbols
Csf1r
Immunogen
KLH conjugated synthetic phosphopeptide derived from human CSF1R around the phosphorylation site of tyrosine 723.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Related Products
Description
- CSF1R (colony stimulating factor 1 receptor) is a cytokine that controls the production, differentiation, and function of macrophages
- CSF1R mediates most if not all of the biological effects of CSF1
- Ligand binding activates the receptor kinase through a process of oligomerization and transphosphorylation
- CSF1R is a tyrosine kinase transmembrane receptor and member of the CSF1/PDGF receptor family of tyrosine-protein kinases
- Mutations in the gene encoding CSF1R have been associated with a predisposition to myeloid malignancy.Tyrosine-protein kinase that acts as cell-surface receptor for CSF1 and IL34 and plays an essential role in the regulation of survival, proliferation and differentiation of hematopoietic precursor cells, especially mononuclear phagocytes, such as macrophages and monocytes
- Promotes the release of proinflammatory chemokines in response to IL34 and CSF1, and plays an important role in innate immunity and in inflammatory processes
- The first intron of the CSF1R gene contains a transcriptionally inactive ribosomal protein L7 processed pseudogene oriented in the opposite direction
- Mutations in the CSF1R gene have been associated with a predisposition to myeloid malignancy.