Phospho-MARK2 (Thr595)Rabbit anti-Bovine, Canine, Human, Mouse, Rat, Polyclonal, Rockland™
Manufacturer: Rockland Immunochemicals
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 50-199-1847-Each-of-1 | In Stock | ₹ 52,930.08 |
50-199-1847 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 52,930.08
GST (18%): ₹ 9,527.414
Total Price: ₹ 62,457.494
Antigen
Phospho-MARK2 (Thr595)
Classification
Polyclonal
Conjugate
Unconjugated
Gene
MARK2
Gene Alias
ELKL motif kinase; ELKL motif kinase 1; Emk; EMK1; EMK-1; MAP/microtubule affinity regulating kinase 2; MAP/microtubule affinity-regulating kinase 2; MARK2; mark2 {ECO:0000312; MGC99619; microtubule affinity regulating kinase 2; OTTHUMP00000218338; OTTHUMP00000218339; OTTHUMP00000218340; OTTHUMP00000218343; Par-1; PAR1 homolog; PAR1 homolog b; Par1b; Par-1b; RGD:708483}; Ser/Thr protein kinase PAR-1B; serine/threonine kinase; serine/threonine protein kinase EMK; Serine/threonine-protein kinase MARK2; testicular tissue protein Li 117
Host Species
Rabbit
Regulatory Status
RUO
Gene ID (Entrez)
13728, 2011, 483769, 535197, 60328
Content And Storage
-20°C, Avoid Freeze/Thaw Cycles
Form
Liquid
Applications
ELISA, Immunofluorescence, Western Blot
Concentration
1 mg/mL
Formulation
0.02M potassium phosphate with 0.15M NaCl and 0.01% sodium azide; pH 7.2
Gene Accession No.
O08679, Q05512, Q7KZI7
Gene Symbols
MARK2
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Bovine, Canine, Human, Mouse, Rat
Product Type
Antibody
Related Products
Description
- Store vial at -20°C prior to opening
- Aliquot contents and freeze at -20°C or below for extended storage
- Avoid cycles of freezing and thawing
- Centrifuge product if not completely clear after standing at room temperature
- This product is stable for several weeks at 4°C as an undiluted liquid
- Dilute only prior to immediate use
- MARK2 pT595 affinity purified antibody is directed against the phosphorylated form of human MARK2 at the pT595 residue
- Reactivity occurs against human MARK2 pT595 protein and the antibody is specific for the phosphorylated form of the protein
- Reactivity with non-phosphorylated human MARK2 is minimal by ELISA
- Expect at least partial reactivity with other isoforms of MARK
- The immunogen sequence is present in all forms identified to date and localizes to T595 on MARK2, T587 on MARK3, T591 on MARK1 and T568 on MARK4
- A BLAST analysis was used to suggest reactivity with this protein from human, dog, bovine, mouse and rat sources based on 100% homology for the immunogen sequence
- Cross reactivity with MARK2 homologues from other sources has not been determined
- EMK (ELKL Motif Kinase) is a small family of ser/thr protein kinases involved in the control of cell polarity, microtubule stability and cancer
- Several cDNA clones have been isolated that encoded two isoforms of the human ser/thr protein kinase EMK1
- These isoforms were characterized by the presence of a 162-bp alternative exon that gave rise to two forms, one containing the exon and the other one lacking it
- Both forms were found to be coexpressed in a number of selected cell lines and tissue samples
- The human EMK1 was shown to be encoded by a single mRNA ubiquitously expressed.