IL-17AF Monoclonal Antibody (20LJS09), PE, eBioscience™, Invitrogen™
Manufacturer: Invitrogen
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each | 50-245-537-Each | In Stock | ₹ 20,883.85 |
50-245-537 - Each
In Stock
Quantity
1
Base Price: ₹ 20,883.85
GST (18%): ₹ 3,759.093
Total Price: ₹ 24,642.943
Antigen
IL-17AF
Classification
Monoclonal
Concentration
5 μL/Test
Formulation
PBS with 0.2% BSA and 0.09% sodium azide; pH 7.2
Gene Accession No.
Q16552, Q96PD4
Gene Symbols
Il17a, Il17f
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
112744, 3605
Content And Storage
4° C, store in dark, DO NOT FREEZE!
Form
Liquid
Applications
Flow Cytometry
Clone
20LJS09
Conjugate
PE
Gene
Il17a
Gene Alias
C87042; CANDF6; Ctla8; CTLA-8; cytokine ML-1; Cytotoxic T-lymphocyte-associated antigen 8; cytotoxic T-lymphocyte-associated protein 8; il 17; IL17; IL-17; Il17a; IL-17A; IL17F; IL-17F; ILN; Interleukin; interleukin 17 (cytotoxic T-lymphocyte-associated serine esterase 8); interleukin 17A; interleukin 17F; interleukin-17A; Interleukin-17F; ML1; ML-1
Host Species
Mouse
Quantity
100 Tests
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG1 κ
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Description
- Description: The 20LJS09 monoclonal antibody reacts with human interleukin (IL)-17AF heterodimer
- This antibody specifically reacts with this heterodimer and has no reactivity for IL-17A or IL-17F homodimers
- IL-17A and IL-17F are well-characterized homodimeric cytokines secreted by T helper 17 (Th17) cells, gamma-delta T cells and several subsets of innate lymphoid cells
- Somewhat less appreciated, IL-17A and IL-17F subunits can also form the heterodimer, IL-17AF
- Together, these three dimers signal through the IL-17RA/IL-17RC receptor complex to mediate immune responses at mucosal interfaces and are found at lesion sites in inflammatory bowel disease, asthma, atopic dermatitis and rheumatoid arthritis
- Applications Reported: This 20LJS09 antibody has been reported for use in intracellular staining followed by flow cytometric analysis
- Applications Tested: This 20LJS09 antibody has been pre-titrated and tested on 10 day in vitro-polarized Th17 cells
- This can be used at 5 μL (0.5 μg) per test
- A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL
- Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test
- Excitation: 488-561 nm; Emission: 578 nm; Laser: Blue Laser, Green Laser, Yellow-Green Laser
- Filtration: 0.2 μm post-manufacturing filtered
- IL-17A and IL-17F are well-characterized homodimeric cytokines secreted by T helper 17 (Th17) cells, gamma-delta T cells and several subsets of innate lymphoid cells
- Somewhat less appreciated, IL-17A and IL-17F subunits can also form the heterodimer, IL-17AF
- Together, these three dimers signal through the IL-17RA/IL-17RC receptor complex to mediate immune responses at mucosal interfaces and are found at lesion sites in inflammatory bowel disease, asthma, atopic dermatitis and rheumatoid arthritis.