Collagen IV Monoclonal Antibody (1042), eFluor™ 660, eBioscience™, Invitrogen™
Manufacturer: Invitrogen
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each | 50-255-0787-Each | In Stock | ₹ 32,809.85 |
50-255-0787 - Each
In Stock
Quantity
1
Base Price: ₹ 32,809.85
GST (18%): ₹ 5,905.773
Total Price: ₹ 38,715.623
Antigen
Collagen IV
Classification
Monoclonal
Concentration
0.2 mg/mL
Formulation
PBS with 0.09% sodium azide, pH 7.2
Gene Accession No.
P02462, P08572, P29400, P53420, Q01955
Gene Symbols
COL4A1, COL4A2, Col4a3, COL4A4, COL4A5
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
1282, 1284, 1285, 1286, 1287
Content And Storage
4°, C, store in dark, DO NOT FREEZE!
Isotype
IgG2b κ
Applications
Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin)
Clone
1042
Conjugate
eFluor 660
Gene
COL4A2
Gene Alias
[a]3(IV), [a]4(IV), alpha 1 type IV collagen, alpha type IV collagen basement membrane, alpha1(IV) collagen, alpha-2 collagen type IV, alpha-3 type IV collagen, alpha3(IV), Arresten, Bru, BSVD, CA44, Canstatin, Col4a1, Col4a-1, COL4A1 NC1 domain, Col4a2, Col4a-2, COL4A3, col4a4, Collagen 4, Collagen alpha-1(IV) chain, collagen alpha-2(IV) chain, Collagen alpha-3(IV) chain, collagen alpha-4(IV) chain, collagen IV, alpha-1 polypeptide, collagen IV, alpha-3 polypeptide, Collagen IV, alpha-4 polypeptide, collagen of basement membrane, alpha-1 chain, collagen of basement membrane, alpha-4 chain, collagen type IV alpha 1 chain, collagen type IV alpha 2, collagen type IV alpha 2 chain, collagen type IV alpha 3 chain, collagen type IV alpha 4 chain, collagen type IV alpha3 chain, collagen, type IV, alpha 1, collagen, type IV, alpha 2, collagen, type IV, alpha 3, collagen, type IV, alpha 3 (Goodpasture antigen), collagen, type IV, alpha 4, Del(8)44H, Del(8)Bru44H, E130010M05Rik, Goodpasture antigen, ICH, LOW QUALITY PROTEIN: collagen alpha-1(IV) chain, LOW QUALITY PROTEIN: collagen alpha-3(IV) chain, LOW QUALITY PROTEIN: collagen alpha-4(IV) chain, POREN2, procollagen alpha1(IV), procollagen, type IV, alpha 1, procollagen, type IV, alpha 2, procollagen, type IV, alpha 3, procollagen, type IV, alpha 4, RATOR, Raw, retinal anterior wiring, Svc, tumstatin, Type IV Collagen
Host Species
Mouse
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Human
Form
Liquid
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Description
- This monoclonal antibody 1042 recognizes human collagen Type IV
- Collagens are the main components of the extracellular matrix and provide the tensile strength to tissues
- There are four main types of collagen (I, II, III and IV) which contribute to the connective tissue
- Expression of type IV is restricted to the basal lamina
- It contains two alpha-1 and one alpha-2-like chains
- Collagen Type IV is associated with disorders such as Alport syndrome and Goodpasture's syndrome
- Applications Reported: This 1042 antibody has been reported for use in immunohistochemical staining, immunohistochemical staining of frozen tissue sections, and immunohistochemical staining of formalin-fixed paraffin embedded tissue sections
- Applications Tested: This 1042 antibody has been tested by immunohistochemistry on formalin-fixed paraffin embedded human tissue using low pH antigen retrieval and can be used at less than or equal to 10 μg/mL
- It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest
- eFluor™ 660 is a replacement for Alexa Fluor™ 647
- eFluor™ 660 emits at 659 nm and is excited with the red laser (633 nm)
- Please make sure that your instrument is capable of detecting this fluorochome
- Excitation: 633-647 nm; Emission: 668 nm; Laser: Red Laser
- Filtration: 0.2 μm post-manufacturing filtered
- Collagen IV is a type of collagen protein that is a major component of the basement membrane in various tissues, including the kidneys, lungs, and skin
- It forms a network-like structure that provides support and stability to the surrounding tissue
- Collagen IV is composed of three alpha chains, which are encoded by the COL4A1, COL4A2, and COL4A3 genes
- Mutations in these genes can lead to various genetic disorders, such as Alport syndrome and Goodpasture syndrome, which affect the kidneys and lungs, respectively.