CD88 (C5aR1) Monoclonal Antibody (S5/1), Alexa Fluor™ 647, eBioscience™, Invitrogen™
Manufacturer: Invitrogen
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each | 51-088-842-Each | In Stock | ₹ 29,427.85 |
51-088-842 - Each
In Stock
Quantity
1
Base Price: ₹ 29,427.85
GST (18%): ₹ 5,297.013
Total Price: ₹ 34,724.863
Antigen
CD88 (C5aR1)
Classification
Monoclonal
Concentration
5 μL/Test
Formulation
PBS with 0.2% BSA and 0.09% sodium azide; pH 7.2
Gene Accession No.
P21730
Gene Symbols
C5AR1
Immunogen
BSA-Conjugated Peptide aa. 1-31
Quantity
100 Tests
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG2a κ
Applications
Flow Cytometry
Clone
S5/1
Conjugate
Alexa Fluor 647
Gene
C5AR1
Gene Alias
anaphylatoxin C5a receptor; C5A; C5a anaphylatoxin chemotactic receptor; C5a anaphylatoxin chemotactic receptor 1; C5a anaphylatoxin receptor; C5a ligand; C5a Receptor; C5AR; C5a-R; C5AR1; C5r1; Cd88; CD88 antigen; complement C5a receptor; complement C5a receptor 1; complement component 5 receptor 1; complement component 5, receptor 1; complement component 5a receptor 1; D7Msu1
Host Species
Mouse
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
728
Content And Storage
4° C, store in dark, DO NOT FREEZE!
Form
Liquid
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Description
- Description: This S5/1 monoclonal antibody recognizes human CD88 also known as C5aR1
- C5aR1 is a complement receptor widely expressed on cells of the myeloid lineage
- Clone S5/1 has been reported to block C5a binding
- Applications Reported: This S5/1 antibody has been reported for use in flow cytometric analysis
- Applications Tested: This S5/1 antibody has been pre-diluted and tested by flow cytometric analysis of normal human peripheral blood cells
- This may be used at 5 μL (0.25 μg) per test
- A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL
- Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test
- Excitation: 633-647 nm; Emission: 668 nm; Laser: Red Laser CD88, also known as C5aR1, is a C5a Anaphylatoxin Receptor that mediates the effects of one of the most potent chemotactic agents known
- C5AR1 has been implicated in asthma, and its expression has been reported in myeloid blood cells, brain, liver, lung, spleen, heart, kidney, and intestinal tract
- CD88 is the receptor for the chemotactic and inflammatory peptide anaphylatoxin C5a
- Functionally, CD88 stimulates chemotaxis, granule enzyme release and superoxide anion production
- CD88 is also a component of the classical pathway of the complement cascade; it may be involved with tissue injury associated with ischemia or sepsis and it may be a component of the membrane attack complex
- Diseases associated with CD88 include Mannose-Binding Lectin Deficiency and Systemic Lupus Erythematosus.