Kallikrein 3/PSA Antibody (KLK3/1248), Novus Biologicals™

Kallikrein 3/PSA

0.2mg/mL

Flow Cytometry, Immunohistochemistry (Paraffin), SDS-Page, Immunofluorescence

Unconjugated

Mouse

Cancer, Cellular Markers, Prostate Cancer, Tumor Biomarkers

10mM PBS and 0.05% BSA with 0.05% Sodium Azide

354

Recombinant full-length human KLK3 protein

Primary

Store at 4C.

33.5 kDa

KLK3/1248

Flow Cytometry 0.5 - 1 ug/million cells in 0.1 ml, Immunohistochemistry-Paraffin 0.5 - 1.0 ug/ml, SDS-Page, Immunofluorescence 0.5 - 1.0 ug/ml

Monoclonal

Purified

RUO

Human

APS seminin, EC 3.4.21, EC 3.4.21.77, Gamma-seminoprotein, hK3, kallikrein 3, (prostate specific antigen), Kallikrein-3, kallikrein-related peptidase 3, KLK2A1, P-30 antigen, prostate specific antigen, prostate-specific antigen, PSA, PSA semenogelase, Semenogelase, Seminin

KLK3

IgG1 κ

Protein A or G purified

Recognizes a single protein of 33-34kDa, identified as the prostate specific antigen (PSA). This MAb is highly specific to PSA and stains prostatic secretory and ductal epithelium in both normal and neoplastic tissues. PSA is a chymotrypsin-like serine protease (kallikrein family) exclusively produced by the prostate epithelium, and abundant in seminal fluid. PSA can be detected in the sera of patients with prostatic carcinoma. It is predominantly complexed to a liver-derived serine protease inhibitor, alpha-1-antichymotrypsin (ACT). A higher proportion of serum PSA is complexed to ACT in prostate cancer than in benign prostate hyperplasia. This MAb makes an excellent pair with MAb A67-B/E3 for PSA tests.