Von Willebrand Factor Antibody (IIIE2.34), Novus Biologicals™

Von Willebrand Factor

0.2 mg/mL

Western Blot, Flow Cytometry, Immunoprecipitation, Immunohistochemistry (Paraffin), Immunofluorescence

Unconjugated

Mouse

Cancer

10mM PBS and 0.05% BSA with 0.05% Sodium Azide

coagulation factor VIII VWF, F8, F8VWF, von Willebrand factor, VWD, vWF

VWF

IgG1 κ

Protein A or G purified

Von Willebrand Factor (vWF) is a multimeric glycoprotein that is found in endothelial cells, plasma and platelets. It acts as a carrier protein for Factor VIII and promotes platelet adhesion and aggregation. vWF undergoes a variety of posttranslational modifications that influence the affinity and availability for Factor VIII, including cleavage of the propeptide and formation of N-terminal disulfide bonds. This antibody helps to establish the endothelial nature of some lesions of disputed histogenesis, e.g. Kaposi's sarcoma and cardiac myxoma. It is widely used for differentiating vascular lesions from those of other tissue differentiation within a panel of other vascular markers although not all tumors of endothelial differentiation contain this antigen.

IIIE2.34

Western Blot 0.5 - 1.0 ug/ml, Flow Cytometry 0.5 - 1 ug/million cells in 0.1 ml, Immunoprecipitation 0.5 - 1 ug/500 ug Protein Lysate, Immunohistochemistry-Paraffin 0.5 - 1.0 ug/ml, Immunofluorescence 0.5 - 1.0 ug/ml

Monoclonal

Purified

RUO

Human

P04275

7450

Recombinant human vWF fragment spanning aa 845-949

Primary

Store at 4C.

250 kDa