MUC6 Antibody (SPM598), Novus Biologicals™
Mouse Monoclonal Antibody
Manufacturer: Fischer Scientific
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Antigen
Gastric Mucin
Concentration
0.2mg/mL
Applications
Flow Cytometry, Immunohistochemistry (Paraffin), Immunofluorescence
Conjugate
Unconjugated
Host Species
Mouse
Target Species
Human
Gene Alias
Gastric mucin-6, MUC-6, mucin 6, gastric, mucin 6, oligomeric mucus/gel-forming, mucin-6
Gene Symbols
MUC6
Isotype
IgG1 κ
Purification Method
Protein A or G purified
Test Specificity
The MUC6 gastric mucin is a secreted glycoprotein that plays an essential role in epithelial cyto-protection from acid, proteases, pathogenic microorganisms, and mechanical trauma in the gastrointestinal tract. Mucin 6 expression is highest in the stomach and gall bladder, with lower expression in the terminal ileum and right colon. In gastric cancer, Mucin 6 has an altered expression. In normal stomach, Mucin 6 is associated with Lewis type 2; Mucin 6 is also expressed in gastric metaplasia, duodenum and pancreas. Mucin 6 is a secretory mucin, located in the deeper mucosal folds of human gall bladder, and its expression is altered with increasing degrees of inflammation.
Clone
SPM598
Dilution
Flow Cytometry 0.5 - 1 ug/million cells in 0.1 ml, Immunohistochemistry-Paraffin 2 - 4 ug/ml, Immunofluorescence 1 - 2 ug/ml
Classification
Monoclonal
Form
Purified
Regulatory Status
RUO
Formulation
10mM PBS and 0.05% BSA with 0.05% Sodium Azide
Gene ID (Entrez)
4588
Immunogen
A synthetic peptide of the Gastric Mucin 6 tandem repeat sequence.
Primary or Secondary
Primary
Content And Storage
Store at 4C.
Molecular Weight of Antigen
252 kDa
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Description
- Ensure accurate, reproducible results in Flow Cytometry, Immunohistochemistry (Paraffin), Immunofluorescence MUC6 Monoclonal specifically detects MUC6 in Human samples
- It is validated for Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin, Immunofluorescence.