gp96/HSP90B1/GRP94 Antibody (9G10.F8.2), Novus Biologicals™

gp96/HSP90B1/GRP94

0.2mg/mL

Western Blot, Flow Cytometry, Immunohistochemistry (Paraffin), Immunofluorescence

Unconjugated

Rat

Cancer, Cellular Markers, ER Markers, Golgi Apparatus Markers, Hypoxia, Membrane Trafficking and Chaperones

10mM PBS and 0.05% BSA with 0.05% Sodium Azide

7184

Purified glucose regulated protein 94 (grp94) from chicken oviducts

Primary

Store at 4C.

94 kDa

9G10.F8.2

Western Blot 0.5 - 1.0 ug/ml, Flow Cytometry 0.5 - 1 ug/million cells in 0.1 ml, Immunohistochemistry-Paraffin 0.5 - 1.0 ug/ml, Immunofluorescence 0.5 - 1.0 ug/ml

Monoclonal

Purified

RUO

Human, Mouse, Rat, Porcine, Canine, Chicken, Equine, Guinea Pig, Hamster, Monkey, Primate, Rabbit, Sheep, Xenopus species

94 kDa glucose-regulated protein, endothelial cell (HBMEC) glycoprotein, glucose regulated protein, 94 kDa, GP96ECGP, GRP-94, GRP94gp96 homolog, Heat shock protein 90 kDa beta member 1, heat shock protein 90kDa beta (Grp94), member 1, TRA1endoplasmin, tumor rejection antigen (gp96) 1, Tumor rejection antigen 1, Tumor rejection antigen-1 (gp96)

HSP90B1

IgG2a κ

Protein A or G purified

Recognizes a protein of 94kDa, which is identified as the glucose-regulated protein 94 (grp94) and also tumor rejection antigen (gp96). Grp94 shows a high degree of sequence homology with the heat shock protein 90 (hsp90). This MAb is highly specific to grp94 and shows minimal cross-reaction with other members of the HSP90 family. Grp s are a class of proteins unresponsive to heat shock and are induced by glucose deprivation. Grp94 has been briefly studied as a prognostic factor in breast cancer.