70-194-8
OTX2 Recombinant Rabbit Monoclonal Antibody (14H14L5), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 70-194-8-Each-of-1 | In Stock | ₹ 56,604.00 |
70-194-8 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 56,604.00
GST (18%): ₹ 10,188.72
Total Price: ₹ 66,792.72
Antigen
OTX2
Classification
Recombinant Monoclonal
Concentration
0.5 mg/mL
Formulation
PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.
P32243, P80206, Q64201
Gene Symbols
OTX2
Immunogen
Peptides corresponding to Human OTX2 (aa 20-39, 276-289)
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Applications
Immunocytochemistry, Western Blot
Clone
14H14L5
Conjugate
Unconjugated
Gene
OTX2
Gene Alias
CPHD6; E130306E05Rik; homeobox Otx2; homeobox protein OTX2; MCOPS5; orthodenticle homeobox 2; orthodenticle homolog 2; OTX; OTX2
Host Species
Rabbit
Purification Method
Protein A
Regulatory Status
RUO
Gene ID (Entrez)
18424, 305858, 5015
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Related Products
Description
- This antibody is predicted to react with Rat, Mouse, Pig and Sheep
- Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems
- The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits
- Then, individual clones are screened to select the best candidates for production
- The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire
- OTX2 is a 289 amino acid containing protein encoding a member of the bicoid sub-family of homeodomain-containing transcription factors
- It has two known alternative splice variants with distinct isoforms though presence of other isoforms cannot be excluded
- The protein is an early marker of endodermal differentiation of embryonic stem cells and may play a role in the development of the brain and the sensory organs
- The protein may bind to BCD target sequence (BTS): 5-'TCTAATCCC-3'
- Defects in OTX2 are the cause of microphthalmia syndromic type 5 (MCOPS5).