71-083-7

Phospho-Cdc25A (Ser18) Recombinant Polyclonal Antibody (20HCLC), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 71-083-7-Each-of-1 In Stock ₹ 53,489.00

71-083-7 - Each of 1

₹ 53,489.00

In Stock

Quantity

1

Base Price: ₹ 53,489.00

GST (18%): ₹ 9,628.02

Total Price: ₹ 63,117.02

Antigen

Phospho-Cdc25A (Ser18)

Classification

Recombinant Polyclonal

Concentration

0.5 mg/mL

Formulation

PBS with 0.09% sodium azide; pH 7.2

Gene Accession No.

P30304

Gene Symbols

CDC25A

Immunogen

Peptide corresponding to Human CDC25A (aa 14-21)

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

Applications

Immunocytochemistry, Western Blot

Clone

20HCLC

Conjugate

Unconjugated

Gene

CDC25A

Gene Alias

CDC25 isoform A1-CAG; CDC25A; CDC25A2; CDC25A2-CAG isoform; Cdc25m3; cell division cycle 25A; D9Ertd393e; dual specificity phosphatase Cdc25A; EC 3.1.3.48; M-phase inducer phosphatase 1; MPIP1

Host Species

Rabbit

Purification Method

Protein A

Regulatory Status

RUO

Gene ID (Entrez)

993

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

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Description

  • This antibody is predicted to react with Monkey and Bovine
  • Recombinant rabbit polyclonal antibodies are unique offerings from Thermo Fisher Scientific
  • They are comprised of a selection of multiple different recombinant monoclonal antibodies, providing the best of both worlds - the sensitivity of polyclonal antibodies with the specificity of monoclonal antibodies - all delivered with the consistency only found in a recombinant antibody
  • While functionally the same as a polyclonal antibody - recognizing multiple epitope sites on the target and producing higher detection sensitivity for low abundance targets - a recombinant rabbit polyclonal antibody has a known mixture of light and heavy chains
  • The exact population can be produced in every lot, circumventing the biological variability typically associated with polyclonal antibody production
  • CDC25a is a member of the CDC25 family of phosphatases
  • Three CDC25 genes are present in human cells: CDC25A, CDC25B, and CDC25C
  • These three genes function at different phases of the cell cycle
  • CDC25a is required for progression through G1 and S phases of the cell cycle
  • CDC25a activates the cyclin-dependent kinase CDC2 by removing two phosphate groups
  • CDC25A is specifically degraded in response to DNA damage, which prevents cells with chromosomal abnormalities from progressing through cell division
  • CDC25A is an oncogene, although its exact role in oncogenesis has not been demonstrated.