GM-CSF Monoclonal Antibody (MP1-31G6), Biotin, eBioscience™, Invitrogen™
Rat Monoclonal Antibody
Manufacturer: Fischer Scientific
The price for this product is unavailable. Please request a quote
Antigen
GM-CSF
Concentration
0.5 mg/mL
Classification
Monoclonal
Form
Liquid
Regulatory Status
RUO
Formulation
PBS with 0.09% sodium azide; pH 7.2
Gene Alias
colony stimulating factor 2; colony stimulating factor 2 (granulocyte-macrophage); colony-stimulating factor; CSF; CSF2; Csfgm; cytokine; GMCSF; Gm-CSf; granulocyte macrophage colony stimulating factor; granulocyte macrophage-colony stimulating factor; granulocyte-macrophage colony stimulating factor 2; granulocyte-macrophage colony-stimulating factor; MGC131935; MGC138897; MGC151255; MGC151257; MGI-IGM; M-GM-CSF; molgramostin; put. GM-CSF; sargramostim
Gene Symbols
CSF2
Primary or Secondary
Primary
Content And Storage
4° C, do not freeze
Gene
CSF2
Clone
MP1-31G6
Applications
ELISA
Conjugate
Biotin
Host Species
Rat
Target Species
Mouse
Gene Accession No.
P01587
Gene ID (Entrez)
12981
Isotype
IgG1 κ
Purification Method
Affinity chromatography
Product Type
Antibody
Related Products
Description
- Description: The MP1-31G6 antibody reacts with mouse granulocyte/macrophage - colony stimulating factor (GM-CSF), a 14 kDa cytokine secreted by activated T cells and macrophages
- Applications Reported: MP1-31G6 has been reported for use in detection of mouse GM-CSF by ELISA
- Applications Tested: The MP1-31G6 antibody has been tested as the detection antibody in a sandwich ELISA for analysis of mouse GM-CSF (Granulocyte/Macrophage-Colony Stimulating Factor, GMCSF) in combination with the purified MP1-22E9 (14-7331) antibody for capture and recombinant mouse GM-CSF (14-8331) as the standard
- A suitable range of concentrations of this antibody for ELISA detection is 0.5-2 μg/mL
- A standard curve consisting of doubling dilutions of the recombinant standard over the range of 1000 pg/mL - 8 pg/mL should be included in each ELISA plate
- Filtration: 0.2 μm post-manufacturing filtered
- The GM-CSF gene encodes for a cytokine that regulates the production, differentiation, and function of macrophages and granulocytes
- The active form of the protein exists as a homodimer in the extracellular space
- This gene is located in a cluster of related genes at the chromosome region 5q31, which has been associated with interstitial deletions in the 5q- syndrome and acute myelogenous leukemia
- Other genes in the cluster include interleukins 4, 5, and 13
- The gene is involved in promoting tissue inflammation
- Elevated levels of cytokines, including the one produced by this gene, have been observed in SARS-CoV-2 infected patients with acute respiratory distress syndrome
- Mice that lack this gene or its receptor have been shown to develop pulmonary alveolar proteinosis.