7105435

Integrin alpha L/CD11a Antibody (CRIS-3), Novus Biologicals™

Mouse Monoclonal Antibody

Manufacturer: Fischer Scientific

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Antigen

Integrin alpha L/CD11a

Dilution

Flow Cytometry 0.5-1ug/million cells, Immunocytochemistry/Immunofluorescence 0.5-1ug/ml, Immunohistochemistry-Frozen 0.5-1.0ug/ml, SDS-Page

Classification

Monoclonal

Form

Purified

Regulatory Status

RUO

Target Species

Human

Gene Accession No.

P20701

Gene ID (Entrez)

3683

Immunogen

Stimulated human leukocytes

Primary or Secondary

Primary

Content And Storage

Store at 4C.

Molecular Weight of Antigen

180 kDa

Clone

CRIS-3

Applications

Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Frozen), SDS-Page

Conjugate

Unconjugated

Host Species

Mouse

Research Discipline

Adaptive Immunity, Cellular Markers, Cytokine Research, Hematopoietic Stem Cell Markers, Immunology, Myeloid Cell Markers, Signal Transduction, Stem Cell Markers

Formulation

PBS with 0.05% BSA. with 0.05% Sodium Azide

Gene Alias

CD11 antigen-like family member A, CD11a antigen, CD11Aantigen CD11A (p180), lymphocyte function-associated antigen 1, alphapolypeptide, integrin alpha-L, integrin gene promoter, integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen1; alpha polypeptide), Leukocyte adhesion glycoprotein LFA-1 alpha chain, Leukocyte function-associated molecule 1 alpha chain, LFA-1, LFA-1 alpha, LFA1A, LFA-1A, lymphocyte function-associated antigen 1

Gene Symbols

ITGAL

Isotype

IgG2b κ

Purification Method

Protein A purified

Test Specificity

Recognizes a protein of 180kDa, identified as CD11a (Leucocyte Workshop II; Code N202). CD11a complex with the 2 subunit of the integrin family, CD18, to form the cell surface heterodimer, LFA-1 or CD11a/C18 (aLbL). LFA-1 is expressed on all leukocytes including lymphocytes, monocytes, and granulocytes. It is involved in leukocyte adhesion to its ligands including intercellular adhesion molecule-1 (ICAM-1 or CD54), ICAM-2 (CD102), ICAM-3 (CD50) and Telencephalin (TLN) and play a role in most immune/inflammatory responses.

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Description

  • Integrin alpha L/CD11a Monoclonal specifically detects Integrin alpha L/CD11a in Human samples
  • It is validated for Flow Cytometry, Immunocytochemistry/Immunofluorescence, Functional.