Factor XIIIa Mouse anti-Human, Clone: F13A1/1448, Novus Biologicals™

Factor XIIIa

0.2 mg/mL

Western Blot, Flow Cytometry, ELISA, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin)

Unconjugated

Mouse

Apoptosis, Cancer, Cell Biology

10mM PBS with 0.05% BSA with 0.05% Sodium Azide

2162

Recombinant fragment of human Factor XIIIa protein (aa46-181) (exact sequence is proprietary)

Primary

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

83 kDa

F13A1/1448

Western Blot 0.5-1.0 ug/ml, Flow Cytometry 0.5-1 ug/million cells, ELISA 2-4 ug/ml, Immunocytochemistry/Immunofluorescence 0.5-1 ug/ml, Immunohistochemistry-Paraffin 1-2 ug/ml, SDS-Page, Protein Array 1:100-1:2000

Monoclonal

Purified

RUO

Human

bA525O21.1 (coagulation factor XIII, A1 polypeptide), coagulation factor XIII A chain, coagulation factor XIII, A1 polypeptide, Coagulation factor XIIIa, EC 2.3.2.13, F13Acoagulation factor XIII, A polypeptide, factor XIIIa, fibrin stabilizing factor, A subunit, fibrinoligase, FSF, A subunit, Protein-glutamine gamma-glutamyltransferase A chain, TGase, Transglutaminase A chain, transglutaminase. plasma

F13A1

IgG2b κ

Protein A or G purified

The specificity of this monoclonal antibody to its intended target was validated by HuProtTM Array, containing more than 19,000, full-length human proteins. It recognizes a protein of 83kDa, which is identified as Factor XIIIa. It has been identified in platelets, megakaryocytes, and fibroblast-like mesenchymal or histiocytic cells in the placenta, uterus, and prostate, monocytes and macrophages and dermal dendritic cells. Anti-factor XIIIa has been found to be useful in differentiating between dermatofibroma (almost all cases are positive), dermatofibrosarcoma protuberans ( -/+) and desmoplastic malignant melanoma (-). Anti-factor XIIIa positivity is also seen in capillary hemagioblastoma, hemangioendothelioma, hemangiopericytoma, xanthogranuloma, xanthoma, hepatocellular carcinoma, glomus tumor, and meningioma.