7144148
Cul3 Polyclonal Antibody, Bethyl Laboratories
Rabbit Polyclonal Antibody
Manufacturer: Fischer Scientific
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Antigen
Cul3
Classification
Polyclonal
Form
Liquid
Regulatory Status
RUO
Formulation
TBS with 0.1% BSA and 0.09% sodium azide
Gene Alias
CUL-3
Gene Symbols
CUL3
Isotype
IgG
Purification Method
Antigen affinity chromatography
Product Type
Antibody
Applications
Immunohistochemistry
Conjugate
Unconjugated
Host Species
Rabbit
Target Species
Human
Gene Accession No.
Q13618
Gene ID (Entrez)
8452
Immunogen
Between 650 and 700
Primary or Secondary
Primary
Content And Storage
4° C
Gene
CUL3
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Description
- The recommended shelf life for this product is 1 year from date of receipt
- Based on 100% sequence identity, this antibody is predicted to react with Mouse, Rat, Zebrafish, X
- laevis, X
- tropicalis, Chicken, Turkey, Bovine, Dog, Horse, Rabbit, Gui Cullin 3 is a member of the family of human cullin genes (CUL 1, 2, 3, 4a, 4b, and 5) homologous to the S
- cerevisiae cdc 53 gene
- CUL 1 forms a complex with human p19 skp1 and F box protein p45 skp2
- Together with cdc 53 (Known as Cul A), as three subunits, they form a ubiquitin ligase-controlling proteolysis of G1 cell cycle regulatory proteins
- In contrast to CUL 1, CUL 2 does not associate with p19 skp1 and p45 skp2
- Instead, CUL 2 forms a complex with an inactive transcriptional elongation complex, SIII, formed by three subunits: Elongain C, Elongin B and VHL
- The function of this association remains unknown.