7144204

CAD Polyclonal Antibody, Bethyl Laboratories

Rabbit Polyclonal Antibody

Manufacturer: Fischer Scientific

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Antigen

CAD

Classification

Polyclonal

Form

Liquid

Regulatory Status

RUO

Formulation

TBS with 0.1% BSA and 0.09% sodium azide

Gene Alias

CAD protein, CAD trifunctional protein, multifunctional protein CAD

Gene Symbols

CAD

Isotype

IgG

Purification Method

Antigen affinity chromatography

Product Type

Antibody

Applications

Immunofluorescence, Immunohistochemistry

Conjugate

Unconjugated

Host Species

Rabbit

Target Species

Human

Gene Accession No.

P27708

Gene ID (Entrez)

790

Immunogen

Between 1650 and 1700

Primary or Secondary

Primary

Content And Storage

4° C

Gene

CAD

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Description

  • The recommended shelf life for this product is 1 year from date of receipt
  • Based on 100% sequence identity, this antibody is predicted to react with Mouse, Rat, Dog, Rabbit, Guinea pig_10141, Pig, Orangutan, Monkey, Gorilla, Chimpanzee, Bl The de novo synthesis of pyrimidine nucleotides is required for mammalian cells to proliferate
  • This gene encodes a trifunctional protein which is associated with the enzymatic activities of the first 3 enzymes in the 6-step pathway of pyrimidine biosynthesis: carbamoylphosphate synthetase (CPS II), aspartate transcarbamoylase, and dihydroorotase
  • This protein is regulated by the mitogen-activated protein kinase (MAPK) cascade, which indicates a direct link between activation of the MAPK cascade and de novo biosynthesis of pyrimidine nucleotides.