7144556

BAD Polyclonal Antibody, Bethyl Laboratories

Rabbit Polyclonal Antibody

Manufacturer: Fischer Scientific

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Antigen

BAD

Classification

Polyclonal

Form

Liquid

Regulatory Status

RUO

Formulation

TBS with 0.1% BSA and 0.09% sodium azide

Gene Alias

Bcl-associated death promoter

Immunogen

Between 1 and 50

Primary or Secondary

Primary

Content And Storage

4° C

Gene

BAD

Applications

Immunofluorescence, Immunohistochemistry

Conjugate

Unconjugated

Host Species

Rabbit

Target Species

Human, Mouse

Gene Accession No.

Q61337, Q92934

Gene ID (Entrez)

12015, 572

Isotype

IgG

Purification Method

Antigen affinity chromatography

Product Type

Antibody

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Description

  • The recommended shelf life for this product is 1 year from date of receipt
  • Based on 100% sequence identity, this antibody is predicted to react with Rat, Dog, Panda, Cat, Orangutan, Monkey, Gorilla, Chimpanzee, hirteen-lined ground squirrel and S The protein encoded by this gene is a member of the BCL-2 family
  • BCL-2 family members are known to be regulators of programmed cell death
  • This protein positively regulates cell apoptosis by forming heterodimers with BCL-xL and BCL-2, and reversing their death repressor activity
  • Proapoptotic activity of this protein is regulated through its phosphorylation
  • Protein kinases AKT and MAP kinase, as well as protein phosphatase calcineurin were found to be involved in the regulation of this protein
  • Alternative splicing of this gene results in two transcript variants which encode the same isoform.