7144178

APC Polyclonal Antibody, Bethyl Laboratories

Rabbit Polyclonal Antibody

Manufacturer: Fischer Scientific

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Antigen

APC

Classification

Polyclonal

Form

Liquid

Regulatory Status

RUO

Formulation

TBS with 0.1% BSA and 0.09% sodium azide

Gene Alias

Adenomatous Polyposis Coli, APC, DP2, DP2.5, DP3, FAP, FPC, GS

Gene Symbols

APC

Isotype

IgG

Purification Method

Antigen affinity chromatography

Product Type

Antibody

Applications

Immunohistochemistry

Conjugate

Unconjugated

Host Species

Rabbit

Target Species

Human

Gene Accession No.

P25054

Gene ID (Entrez)

324

Immunogen

Between 1 and 50

Primary or Secondary

Primary

Content And Storage

4° C

Gene

APC

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Description

  • The recommended shelf life for this product is 1 year from date of receipt
  • Based on 100% sequence identity, this antibody is predicted to react with Mouse, Rat, Zebrafish, X
  • tropicalis, Chicken, Bovine, Dog, Horse, Rabbit, Guinea pig_1014 This gene encodes a tumor suppressor protein that acts as an antagonist of the Wnt signaling pathway
  • It is also involved in other processes including cell migration and adhesion, transcriptional activation, and apoptosis
  • Defects in this gene cause familial adenomatous polyposis (FAP), an autosomal domit pre-maligt disease that usually progresses to maligcy
  • Disease-associated mutations tend to be clustered in a small region designated the mutation cluster region (MCR) and result in a truncated protein product.