7144293
Paf1 Polyclonal Antibody, Bethyl Laboratories
Rabbit Polyclonal Antibody
Manufacturer: Fischer Scientific
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Antigen
Paf1
Classification
Polyclonal
Form
Liquid
Regulatory Status
RUO
Gene Alias
F23149_1, PD2, RNA polymerase II-associated factor 1 homolog, hPAF1, pancreatic differentiation protein 2
Isotype
IgG
Purification Method
Antigen affinity chromatography
Product Type
Antibody
Applications
Immunohistochemistry
Conjugate
Unconjugated
Host Species
Rabbit
Formulation
TBS with 0.1% BSA and 0.09% sodium azide
Immunogen
Between 475 and 525
Primary or Secondary
Primary
Content And Storage
4° C
Gene
PAF1
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Description
- The recommended shelf life for this product is 1 year from date of receipt
- PAF is a five-subunit protein complex composed of Paf1, Cdc73, Leo1, Rtf1 and Ctr9, which was first purified from yeast
- The yeast PAF (yPAF) complex interacts with RNA polymerase II and coordinates the setting of histone marks associated with active transcription
- The human PAF (hPAF) complex shares four subunits with yPAF (hCtr9, hPaf1, hLeo1 and Cdc73), but contains an additional higher eukaryotic-specific subunit, hSki8
- In addition to coordinating events during transcription (initiation, promoter clearance and elongation); PAF also coordinates events in RNA quality control.