7144571
MBD3 Polyclonal Antibody, Bethyl Laboratories
Rabbit Polyclonal Antibody
Manufacturer: Fischer Scientific
The price for this product is unavailable. Please request a quote
Antigen
MBD3
Classification
Polyclonal
Form
Liquid
Regulatory Status
RUO
Formulation
TBS with 0.1% BSA and 0.09% sodium azide
Gene Alias
Methyl-CpG-binding protein MBD3
Gene Symbols
MBD3
Isotype
IgG
Purification Method
Antigen affinity chromatography
Product Type
Antibody
Applications
Immunohistochemistry
Conjugate
Unconjugated
Host Species
Rabbit
Target Species
Human
Gene Accession No.
O95983
Gene ID (Entrez)
53615
Immunogen
Between 265 and 291
Primary or Secondary
Primary
Content And Storage
4° C
Gene
MBD3
Related Products
Description
- The recommended shelf life for this product is 1 year from date of receipt
- Based on 100% sequence identity, this antibody is predicted to react with Orangutan, Monkey, Gorilla, Chimpanzee, Northern white-cheeked gibbon and Crab-eating macaque DNA methylation is the major modification of eukaryotic genomes and plays an essential role in mammalian development
- Human proteins MECP2, MBD1, MBD2, MBD3, and MBD4 comprise a family of nuclear proteins related by the presence in each of a methyl-CpG binding domain
- However, unlike the other family members, MBD3 is not capable of binding to methylated DNA
- The predicted MBD3 protein shares 71% and 94% identity with MBD2 and mouse Mbd3
- MBD3 is a subunit of the NuRD, a multisubunit complex containing nucleosome remodeling and histone deacetylase activities
- MBD3 mediates the association of metastasis-associated protein 2 with the core histone deacetylase complex.