7144338
DDX3 Polyclonal Antibody, Bethyl Laboratories
Rabbit Polyclonal Antibody
Manufacturer: Fischer Scientific
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Antigen
DDX3
Classification
Polyclonal
Form
Liquid
Regulatory Status
RUO
Formulation
TBS with 0.1% BSA and 0.09% sodium azide
Gene Alias
DEAD box protein 3, X-chromosomal; Helicase-like protein 2; HLP2; DEAD box; X isoform; DDX3X; DBX
Immunogen
Between 1 and 50
Primary or Secondary
Primary
Content And Storage
4° C
Gene
DDX3X
Applications
Immunohistochemistry
Conjugate
Unconjugated
Host Species
Rabbit
Target Species
Human, Mouse
Gene Accession No.
O00571, Q62167
Gene ID (Entrez)
13205, 1654
Isotype
IgG
Purification Method
Antigen affinity chromatography
Product Type
Antibody
Related Products
Description
- The recommended shelf life for this product is 1 year from date of receipt
- Based on 100% sequence identity, this antibody is predicted to react with Rat, Bovine, Dog, Rabbit, Pig, Golden hamster, Panda, Orangutan, Monkey, Gorilla and White-tufted DDX3 contains all of the motifs of the DEAD-box family of RNA helicases, including the Asp-Glu-Ala-Asp sequence that gives the protein family its name and distinguishes it from other RNA helicases
- DDX3 is localized to the X chromosome and has a highly conserved functional homolog (DBY) on the Y chromosome
- DDX3 is thought to be involved in RNA splicing, RNA transport, and translation initiation
- It has also been shown to be involved in cell growth control and is deregulated in hepatitis virus-associated hepatocellular carcinoma
- Recent experiments suppressing DDX3 expression blocked HIV-1 RNA export from the nucleus, suggesting that DDX3 functions as a shuttling protein that transports the HIV-1 protein Rev and its cofactor CRM1 from the nucleus to the cytoplasm.