7144366

BRG1/SMARCA4 Polyclonal Antibody, Bethyl Laboratories

Rabbit Polyclonal Antibody

Manufacturer: Fischer Scientific

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Antigen

BRG1/SMARCA4

Classification

Polyclonal

Form

Liquid

Regulatory Status

RUO

Formulation

TBS with 0.1% BSA and 0.09% sodium azide

Gene Alias

ATP-dependent helicase SMARCA4; BAF190A; BRG1-associated factor 190A; BRM/SWI2-related gene 1; SNF2-like 4; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 4; brahma protein-like 1; global transcription activator homologous sequence; homeotic gene regulator; mitotic growth and transcription activator; nuclear protein GRB1; protein BRG-1; protein brahma homolog 1; sucrose nonfermenting-like 4; transcription activator BRG1

Immunogen

Between 75 and 125

Primary or Secondary

Primary

Content And Storage

4° C

Gene

SMARCA4

Applications

Immunohistochemistry

Conjugate

Unconjugated

Host Species

Rabbit

Target Species

Human, Mouse

Gene Accession No.

P51532, Q3TKT4

Gene ID (Entrez)

20586, 6597

Isotype

IgG

Purification Method

Antigen affinity chromatography

Product Type

Antibody

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Description

  • The recommended shelf life for this product is 1 year from date of receipt
  • Based on 100% sequence identity, this antibody is predicted to react with Dog, Horse, Rabbit, Panda, Orangutan, Monkey, Gorilla, Chimpanzee, Gray short-tailed opossum and Brg1 (Brahma-related gene 1) is an ATPase subunit of SWI2/SNF2-like chromatin-remodeling complexes that enable access of regulatory and effector proteins in transcription, DNA repair and DNA replication
  • Although Brg1-containing complexes are not essential for general cell survival, they participate in transcriptional regulation of several hundred genes including those involved in interferon and stress response, immune cells differentiation, neurogenesis, cell cycle etc
  • and is absolutely necessary for mouse embryogenesis
  • Brg1 is also involved in cell growth arrest, senescence and tumour supression.