7144407
AKT1 Polyclonal Antibody, Bethyl Laboratories
Rabbit Polyclonal Antibody
Manufacturer: Fischer Scientific
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Antigen
AKT1
Classification
Polyclonal
Form
Liquid
Regulatory Status
RUO
Formulation
TBS with 0.1% BSA and 0.09% sodium azide
Gene Alias
AKT, MGC99656, PKB, PKB-ALPHA, PRKBA, RAC, RAC-ALPHA
Gene Symbols
AKT1
Isotype
IgG
Purification Method
Antigen affinity chromatography
Product Type
Antibody
Applications
Immunohistochemistry
Conjugate
Unconjugated
Host Species
Rabbit
Target Species
Human
Gene Accession No.
P31749
Gene ID (Entrez)
207
Immunogen
Between 25 and 75
Primary or Secondary
Primary
Content And Storage
4° C
Gene
AKT1
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Description
- The recommended shelf life for this product is 1 year from date of receipt
- Based on 100% sequence identity, this antibody is predicted to react with Orangutan, Monkey, Gorilla, Chimpanzee, Northern white-cheeked gibbon, Crab-eating macaque and Wh The Akt family of serine/threonine protein kinases (also called protein kinase B/PKB) plays a key role in insulin signaling, cellular survival, and transformation
- Akt1 is activated by phosphorylation on residues threonine 308 and Serine 473
- Thr308, in the catalytic domain, is phosphorylated by the protein kinase PDK1, and Ser473, in the COOH-terminal regulatory domain, is phosphorylated by putative serine 473 kinase
- To date, a couple of proteins have been shown to physically interact with PKB.