7144471

Prohibitin Polyclonal Antibody, Bethyl Laboratories

Rabbit Polyclonal Antibody

Manufacturer: Fischer Scientific

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Antigen

Prohibitin

Classification

Polyclonal

Form

Liquid

Regulatory Status

RUO

Formulation

TBS with 0.1% BSA and 0.09% sodium azide

Gene Alias

PHB

Gene Symbols

PHB

Isotype

IgG

Purification Method

Antigen affinity chromatography

Product Type

Antibody

Applications

Immunohistochemistry

Conjugate

Unconjugated

Host Species

Rabbit

Target Species

Human

Gene Accession No.

P35232

Gene ID (Entrez)

5245

Immunogen

Between 222 and 272

Primary or Secondary

Primary

Content And Storage

4° C

Gene

PHB

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Description

  • The recommended shelf life for this product is 1 year from date of receipt
  • Based on 100% sequence identity, this antibody is predicted to react with Mouse, Rat, Bovine, Dog, Rabbit, Guinea pig_10141, Pig, Panda, Cat, Orangutan, Monkey, Gor Prohibitin is an evolutionarily conserved gene that is ubiquitously expressed
  • It is thought to be a negative regulator of cell proliferation and may be a tumor suppressor
  • Mutations in PHB have been linked to sporadic breast cancer
  • Prohibitin is expressed as two transcripts with varying lengths of 3' untranslated region
  • The longer transcript is present at higher levels in proliferating tissues and cells, suggesting that this longer 3' untranslated region may function as a trans-acting regulatory RNA.