7144596
CDC6 Polyclonal Antibody, Bethyl Laboratories
Rabbit Polyclonal Antibody
Manufacturer: Fischer Scientific
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Antigen
CDC6
Classification
Polyclonal
Form
Liquid
Regulatory Status
RUO
Formulation
TBS with 0.1% BSA and 0.09% sodium azide
Gene Alias
Cyclin dependent kinase 6, CDC18L, HsCDC18, HsCDC6
Immunogen
Between 1 and 50
Primary or Secondary
Primary
Content And Storage
4° C
Gene
CDC6
Applications
Immunohistochemistry
Conjugate
Unconjugated
Host Species
Rabbit
Target Species
Human, Mouse
Gene Accession No.
O89033, Q99741
Gene ID (Entrez)
23834, 990
Isotype
IgG
Purification Method
Antigen affinity chromatography
Product Type
Antibody
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Description
- The recommended shelf life for this product is 1 year from date of receipt
- Based on 100% sequence identity, this antibody is predicted to react with Gorilla and Chimpanzee The protein encoded by this gene is highly similar to Saccharomyces cerevisiae Cdc6, a protein essential for the initiation of DNA replication
- This protein functions as a regulator at the early steps of DNA replication
- It localizes in cell nucleus during cell cyle G1, but translocates to the cytoplasm at the start of S phase
- The subcellular translocation of this protein during cell cyle is regulated through its phosphorylation by Cdks
- Transcription of this protein was reported to be regulated in response to mitogenic signals through transcriptional control mechanism involving E2F proteins.