7144607
NRIP Polyclonal Antibody, Bethyl Laboratories
Rabbit Polyclonal Antibody
Manufacturer: Fischer Scientific
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Antigen
NRIP
Classification
Polyclonal
Form
Liquid
Regulatory Status
RUO
Formulation
TBS with 0.1% BSA and 0.09% sodium azide
Gene Alias
ARCAP, DCAF6, IQWD1, MSTP055, DDB1- and CUL4-associated factor 6, Androgen receptor complex-associated protein, Nuclear receptor interaction protein, IQ motif and WD repeat-containing protein 1
Gene Symbols
DCAF6
Isotype
IgG
Purification Method
Antigen affinity chromatography
Product Type
Antibody
Applications
Immunohistochemistry
Conjugate
Unconjugated
Host Species
Rabbit
Target Species
Human
Gene Accession No.
Q58WW2
Gene ID (Entrez)
55827
Immunogen
Between 600 and 650
Primary or Secondary
Primary
Content And Storage
4° C
Gene
DCAF6
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Description
- The recommended shelf life for this product is 1 year from date of receipt
- Based on 100% sequence identity, this antibody is predicted to react with Monkey, Gorilla, Chimpanzee, Small-eared galago and White-tufted-ear marmoset NRIP is a novel 860a.a nuclear protein consisting of seven conserved WD40 domains and one NLS motif
- It binds to androgen and glucocorticoid receptors and up regulates their transcriptional activity, thereby functioning as a nuclear receptor coactivator
- Role of NRIP has been implicated in cell growth and also in cervical and prostrate cancer thus indicating a therapeutic intervention
- Northern Blot analysis detected a high expression of NRIP in skeletal muscle and testis and low expression in heart, prostrate and adrenal gland.