EDAR, Rabbit anti-Human,Mouse,Rat,Canine,Chicken, Clone: EDAR12, Novus Biologicals™

EDAR

1 mg/mL

Western Blot, ELISA, Blocking Assay

Unconjugated

Rabbit

Apoptosis

PBS

10913

EDAR12 was prepared by immunixzing female OVE1B mice (with the Edar gene deleted) subcutaneously with mouse EDAR-Fc and positive hybridoma clones were screened for binding mEDAR by ELISA.

Primary

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

EDAR12

Western Blot, ELISA, Surface Plasmon Resonance, Block/Neutralize

Monoclonal

Purified

RUO

Human, Mouse, Rat, Canine, Chicken

Anhidrotic ectodysplasin receptor 1, DLED3, Ectodermal dysplasia receptor, ectodysplasin 1, anhidrotic receptor, ectodysplasin A receptor, Ectodysplasin-A receptor, ED1R, ED5, EDA1R, EDA3EDA-A1 receptor, EDA-A1R, Edar, FLJ94390, HRM1, mouse, homolog of, tumor necrosis factor receptor superfamily member EDAR

EDAR

IgG κ

Protein A purified

EDAR12 recognises and binds to CRD1 of the extracellular domain of mouse EDAR. EDAR3 cross-reacts with EDAR derived from human, dog, rat and chicken when EDAR is fused to the glycosylphosphatidylinositol anchor of TRAILR3. EDAR is the receptor for the TNF family ligand EDA1, which is a type II transmembrane protein possessing a collagen-like domain and a C-terminal TNF-homology domain. EDAR is important for the correct development of skin appendages including hair, teeth and eccrine sweat glands. LoF mutations in the Eda gene is known to cause XLHED (X-linked hypohidrotic ectodermal dysplasia), and results in abnormal development.