Fibrinopeptide B, Rabbit anti-Human, Clone: 800000, Novus Biologicals™

Fibrinopeptide B

1 mg/mL

ELISA

Unconjugated

Rabbit

Cell Cycle and Replication

PBS

2244

8E5 was prepared fusing Sp2/o myeloma cells with spleen cells derived from female BALB/c mice immunized with a synthetic beta-fibrin peptide seqeunce GHRPLDKC conjugated to MB-KLH (maleimidobenzoylated keyhole limpet hemocyanin).

Primary

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

800000

ELISA, In vivo assay

Monoclonal

Purified

RUO

Human

fibrinogen beta chain, fibrinogen, B beta polypeptide, MGC104327, MGC120405

FGB

IgG κ

Protein A purified

8E5 binds to the amino-terminal region of the beta-chain of human fibrin at an epitope consiting of GHRPLDKC. Binding is possible in both the monomeric form and the polymeric form of the protein. This peptide sequence is found only in fibrin, and not in its precursor fibrinogen and so there is no cross-reactivity with fibrinogen. Fibrin is a non-globular protein which plays a role in the clotting of blood and circulates as the precursor fibrinogen. Polymerization occurs through the action of the protease thrombin, which results in the active fibrin. Fibrin polymerizes as an insoluble matrix and forms a clot along with platelets over a wound site.