7188371

SUV39H1 Monoclonal Antibody (MG44), Active Motif™

Mouse Monoclonal Antibody

Manufacturer: Fischer Scientific

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Antigen

SUV39H1

Concentration

1 mg/mL

Classification

Monoclonal

Form

Liquid

Regulatory Status

RUO

Formulation

70mM tris with 0.07mM EDTA, 105mM NaCl, 30% glycerol, 31mM glycine and 0.035% sodium azide; pH 8

Gene Alias

AI852103; AL022883; DXHXS7466e; H3-K9-HMTase 1; Histone H3-K9 methyltransferase 1; Histone-lysine N-methyltransferase SUV39H1; histone-lysine N-methyltransferase, H3 lysine-9 specific 1; KMT1A; Lysine N-methyltransferase 1A; MG44; mIS6; Position-effect variegation 3-9 homolog; RGD1565028; Su(var)3-9 homolog 1; Suppressor of variegation 3-9 homolog 1; suppressor of variegation 3-9 homolog 1 (Drosophila); SUV39H; Suv39h histone methyltransferase; SUV39H1

Gene Symbols

SUV39H1

Isotype

IgG1

Purification Method

Protein G

Product Type

Antibody

Clone

MG44

Applications

ChIP Assay, Immunocytochemistry, Immunofluorescence, Immunoprecipitation, Western Blot

Conjugate

Unconjugated

Host Species

Mouse

Target Species

Human, Mouse

Gene Accession No.

O43463, O54864

Gene ID (Entrez)

20937, 6839

Immunogen

This SUV39H1 antibody was raised against a recombinant protein corresponding to amino acids 1-126 of mouse SUV39H1.

Primary or Secondary

Primary

Content And Storage

-20°C, Avoid Freeze/Thaw Cycles

Gene

SUV39H1

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Description

  • This gene encodes an evolutionarily-conserved protein containing an N-terminal chromodomain and a C-terminal SET domain
  • The encoded protein is a histone methyltransferase that trimethylates lysine 9 of histone H3, which results in transcriptional gene silencing
  • Loss of function of this gene disrupts heterochromatin formation and may cause chromosome instability
  • Alternative splicing results in multiple transcript variants.