SNAI1 / Snail Monoclonal Antibody (9H2), Active Motif™
Rat Monoclonal Antibody
Manufacturer: Fischer Scientific
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Antigen
SNAI1 / Snail
Concentration
1 mg/mL
Classification
Monoclonal
Form
Liquid
Regulatory Status
RUO
Formulation
PBS with 30% glycerol and 0.035% sodium azide; pH 7.5
Gene Alias
AI194338; dJ710H13.1; Protein sna; Protein snail homolog 1; SLUGH2; Sna; Sna protein; Sna1; SNAH; Snai1; SNAIL; snail 1; snail 1 homolog; snail 1 zinc finger protein; snail 1, zinc finger protein; snail family transcriptional repressor 1; snail family zinc finger 1; snail homolog 1; Snail1; Zinc finger protein SNAI1
Gene Symbols
Snai1
Isotype
IgG2a
Purification Method
Protein G
Product Type
Antibody
Clone
9H2
Applications
Immunohistochemistry, Western Blot
Conjugate
Unconjugated
Host Species
Rat
Target Species
Human
Gene Accession No.
O95863
Gene ID (Entrez)
6615
Immunogen
This antibody was raised against a full-length recombinant protein corresponding to human SNAI1.
Primary or Secondary
Primary
Content And Storage
-20°C, Avoid Freeze/Thaw Cycles
Gene
Snai1
Related Products
Description
- Zinc finger protein SNAI1 (SNAIL)is a zinc finger transcriptional repressor which down regulates the expression of the ectodermal gene within the mesoderm and functions to form the mesoderm and neural crest
- It is reported that SNAI1 acts as an important factor of tumor invasion as evidenced by its role in E-cadherin down-regulation and induction of epithelial-mesenchymal transition (EMT)
- In human breast cancer, the expression of SNAI1 and/or the homologous SNAI2 (Slug) has been associated with E-cadherin repression, local or distant metastasis, tumor recurrence, or poor prognosis in different tumor series
- It is also reported that Snail 1 protein in the stromamay be anew putative prognosis marker for colon tumors.