ERR-alpha Polyclonal Antibody, Active Motif™
Rabbit Polyclonal Antibody
Manufacturer: Fischer Scientific
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Antigen
ERR-alpha
Applications
Western Blot
Conjugate
Unconjugated
Host Species
Rabbit
Target Species
Human
Gene Accession No.
P11474
Gene ID (Entrez)
2101
Immunogen
This ERR-alpha antibody was raised against a peptide within the C-terminal region of human ERR alpha.
Primary or Secondary
Primary
Content And Storage
-20°C, Avoid Freeze/Thaw Cycles
Gene
ESRRA
Concentration
Lot-Specific
Classification
Polyclonal
Form
Liquid
Regulatory Status
RUO
Formulation
70mM tris with 0.07mM EDTA, 105mM NaCl, 30% glycerol, 31mM glycine and 0.035% sodium azide; pH 8
Gene Alias
ERR alpha; ERR1; ERRa; ERRalpha; ERR-alpha; Errra; ESRL1; ESRRA; estrogen receptor related 1; Estrogen receptor-like 1; estrogen related receptor alpha; estrogen related receptor, alpha; estrogen-related nuclear receptor alpha; Estrogen-related receptor alpha; estrogen-related receptor, alpha; Estrra; HERR1; Nr3b1; Nuclear receptor subfamily 3 group B member 1; orphan nuclear receptor; Steroid hormone receptor ERR1; Steroid hormone receptor ERR1 (Estrogen-related receptor, alpha) (ERR-alpha) (Estrogen receptor-like 1)
Gene Symbols
ESRRA
Isotype
IgG
Purification Method
Antigen affinity chromatography
Product Type
Antibody
Related Products
Description
- Estrogen-related receptor alpha 1 (ERR alpha, ERR1) is an orphan member of the nuclear hormone receptor superfamily
- All the ERR family members share an almost identical DNA-binding domain, which has 68% amino acid identity with that of estrogen receptor
- This protein binds to an ERR-alpha response element (ERRE) containing a single consensus half-site, 5'-tnaaggtca-3' can bind to the medium-chain acyl coenzyme a dehydrogenase (mcad) response element nrre-1 and may act as an important regulator of mcad promoter
- Studies have shown that ERR1 functions a metabolic regulator and is often expressed in tissues that preferentially metabolize fatty acids
- The corresponding gene for the ERR1 is NR3B1.