7188439

HNF4A Polyclonal Antibody, Active Motif™

Rabbit Polyclonal Antibody

Manufacturer: Fischer Scientific

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Antigen

HNF4A

Applications

Immunocytochemistry, Immunofluorescence, Western Blot

Conjugate

Unconjugated

Host Species

Rabbit

Target Species

Human

Gene Accession No.

P41235

Gene ID (Entrez)

3172

Immunogen

This HNF4A antibody was raised against a peptide derived from the N-terminal region of human HNF4A.

Primary or Secondary

Primary

Content And Storage

-20°C, Avoid Freeze/Thaw Cycles

Gene

HNF4A

Concentration

Lot-Specific

Classification

Polyclonal

Form

Liquid

Regulatory Status

RUO

Formulation

PBS with 30% glycerol and 0.035% sodium azide; pH 7.5

Gene Alias

alpha transcription factor 4; FLJ39654; FRTS4; hepatic nuclear factor 4 alpha; hepatic nuclear factor 4, alpha; hepatocyte nuclear factor 4 alpha; hepatocyte nuclear factor 4, alpha; Hepatocyte nuclear factor 4-alpha; HNF4; Hnf-4; HNF4 alpha; Hnf4a; HNF4a7; HNF4a8; HNF4a9; Hnf4alpha; HNF-4-alpha; HNF4-alpha; HNF4alpha10; HNF4alpha10/11/12; HNF4alpha11; HNF4alpha12; MODY; MODY1; Nr2a1; NR2A21; Nuclear receptor 2A1; Nuclear receptor subfamily 2 group A member 1; TCF; Tcf14; TCF-14; Transcription factor 14; Transcription factor HNF-4

Gene Symbols

HNF4A

Isotype

IgG

Purification Method

Antigen affinity chromatography

Product Type

Antibody

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Description

  • Hepatocyte nuclear factor 4 alpha (HNF4 alpha) is an orphan nuclear receptor
  • HNF4a is expressed in the liver, kidney, intestine, and pancreas
  • Mutation of HNF4a in humans has been associated with maturity-onset diabetes of the young type 1 (MODY1)
  • HNF4 binds to DNA as an exclusive homodimer
  • The HNF4a gene is alternatively spliced and may generate up to nine different isoforms, HNF4a1 through HNF4a9.