7188618

AIB1 / SRC-3 Polyclonal Antibody, Active Motif™

Rabbit Polyclonal Antibody

Manufacturer: Fischer Scientific

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Antigen

AIB1 / SRC-3

Applications

ChIP Assay, Western Blot

Conjugate

Unconjugated

Host Species

Rabbit

Target Species

Human

Gene Accession No.

Q9Y6Q9

Gene ID (Entrez)

8202

Immunogen

This AIB1 antibody was raised against a peptide derived from human AIB1/SRC-3.

Primary or Secondary

Primary

Content And Storage

-20°C, Avoid Freeze/Thaw Cycles

Gene

NCOA3

Concentration

Lot-Specific

Classification

Polyclonal

Form

Liquid

Regulatory Status

RUO

Formulation

70mM tris with 0.07mM EDTA, 105mM NaCl, 30% glycerol, 31mM glycine and 0.035% sodium azide; pH 8

Gene Alias

2010305B15Rik; ACTR; AIB1; AIB-1; Amplified in breast cancer 1 protein; amplified in breast cancer-1 protein homolog; AW321064; BHLHE42; CAGH16; CBP-interacting protein; Class E basic helix-loop-helix protein 42; CTG26; KAT13B; MGC141848; NCOA3; NCoA-3; Nuclear receptor coactivator 3; OTTHUMP00000031716; p/Cip; pCIP; RAC3; RAC-3; Receptor-associated coactivator 3; RP5-1049G16.3; Src3; SRC-3; Steroid receptor coactivator protein 3; Thyroid hormone receptor activator molecule 1; TNRC14; TNRC16; TRAM1; TRAM-1

Gene Symbols

NCOA3

Isotype

IgG

Purification Method

Antigen affinity chromatography

Product Type

Antibody

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Description

  • AIB1-AC3 recognizes AIB1, a member of the SRC-1 family of nuclear receptor coactivators with an apparent molecular weight of 160kDa
  • The AIB1 gene has been mapped to region 20q12 and has been shown to be amplified in breast tumors and pancreatic cancer cell lines
  • AIB1 interacts in a ligand-dependent fashion with the estrogen receptor to enhance estrogen-dependent transcriptional gene activation.