SMARCB1 Monoclonal Antibody (2C2), Active Motif™
Mouse Monoclonal Antibody
Manufacturer: Fischer Scientific
The price for this product is unavailable. Please request a quote
Antigen
SMARCB1
Concentration
1 mg/mL
Classification
Monoclonal
Form
Liquid
Regulatory Status
RUO
Formulation
PBS with 30% glycerol and 0.035% sodium azide; pH 7.5
Gene Alias
AU020204; BAF47; BOS_16829; BRG1-associated factor 47; CSS3; hSNF5; hSNFS; INI1; Integrase interactor 1 protein; malignant rhabdoid tumor suppressor; MRD15; mSNF5; PPP1R144; protein phosphatase 1, regulatory subunit 144; RDT; RTPS1; Sfh1p; SMARCB1; SNF5; SNF5 homolog; SNF5/INI1; SNF5L1; Snr1; sucrose nonfermenting, yeast, homolog-like 1; SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1; SWI/SNF-related matrix-associated protein; SWI10; SWNTS1; TYE4
Gene Symbols
SMARCB1
Isotype
IgG2a
Purification Method
Protein A
Product Type
Antibody
Clone
2C2
Applications
Immunocytochemistry, Immunofluorescence, Western Blot
Conjugate
Unconjugated
Host Species
Mouse
Target Species
Human
Gene Accession No.
Q12824
Gene ID (Entrez)
6598
Immunogen
This antibody was raised against full-length recombinant human SMARCB1 protein.
Primary or Secondary
Primary
Content And Storage
-20°C, Avoid Freeze/Thaw Cycles
Gene
SMARCB1
Related Products
Description
- The SWI-SNF complex is involved in the activation of transcription via the remodeling of nucleosome structure in an ATP-dependent manner
- Brm (also designated SNF2alpha) and Brg-1 (also designated SNF2beta) are the ATPase subunits of the mammalian SWI-SNF complex
- Brm, Brg-1, Ini1 (integrase interactor 1, also designated SNF5), BAF155 (also designated SRG3) and BAF170 are thought to comprise the functional core of the SWI-SNF complex
- Addition of Ini1, BAF155 and BAF170 to Brg-1 appears to increase remodeling activity
- Other complex subunits are thought to play regulatory roles
- hSNF2L and hSNF2H both appear to be homologs of Drosophila ISWI, a Brm related ATPase that is present in chromatin remodeling complexes other than SWI/SNF, including the NURF (nucleosome remodeling factor).