SMARCA4 / BRG1 Monoclonal Antibody (3G4), Active Motif™
Rat Monoclonal Antibody
Manufacturer: Fischer Scientific
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Antigen
SMARCA4 / BRG1
Concentration
1 mg/mL
Classification
Monoclonal
Form
Liquid
Regulatory Status
RUO
Formulation
70mM tris with 0.07mM EDTA, 105mM NaCl, 30% glycerol, 31mM glycine and 0.035% sodium azide; pH 8
Gene Alias
ATP-dependent helicase SMARCA4; b2b508.1Clo; b2b692Clo; BAF190; BAF190A; brahma protein-like 1; Brg1; brg-1; BRG1-associated factor 190A; BRM/SWI2-related gene 1; CSS4; FLJ39786; global transcription activator homologous sequence; homeotic gene regulator; HP1-BP72; hSNF2b; Mitotic growth and transcription activator; MRD16; nuclear protein GRB1; Protein brahma homolog 1; Protein BRG-1; RTPS2; SMARCA4; SNF2; SNF2B; SNF2beta; SNF2-beta; Snf2l4; SNF2LB; SNF2-like 4; sucrose nonfermenting-like 4; SW1/SNF; SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 4; SWI2; Transcription activator BRG1
Gene Symbols
Smarca4
Isotype
IgG2b
Purification Method
Protein G
Product Type
Antibody
Clone
3G4
Applications
Immunocytochemistry, Immunofluorescence, Western Blot
Conjugate
Unconjugated
Host Species
Rat
Target Species
Human, Mouse
Gene Accession No.
P51532, Q3TKT4
Gene ID (Entrez)
20586, 6597
Immunogen
This SMARCA4 / BRG1 antibody was raised against a recombinant protein corresponding to amino acids 214-279 of mouse BRG1.
Primary or Secondary
Primary
Content And Storage
-20°C, Avoid Freeze/Thaw Cycles
Gene
Smarca4
Related Products
Description
- Brg1 (Brahma-related gene 1) is an ATPase subunit of SWI2/SNF2-like chromatin-remodeling complexes that enable access of regulatory and effector proteins in transcription, DNA repair and DNA replication
- Although Brg1-containing complexes are not essential for general cell survival, they participate in transcriptional regulation of several hundred genes including those involved in interferon and stress response, immune cells differentiation, neurogenesis, cell cycle etc
- and is absolutely necessary for mouse embryogenesis
- Brg1 is also involved in cell growth arrest, senescence and tumour supression.