7188506

IRF-2 Polyclonal Antibody, Active Motif™

Rabbit Polyclonal Antibody

Manufacturer: Fischer Scientific

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Antigen

IRF-2

Applications

Western Blot

Conjugate

Unconjugated

Host Species

Rabbit

Target Species

Human

Gene Accession No.

P14316

Gene ID (Entrez)

3660

Immunogen

This IRF-2 antibody was raised against a peptide within the C-terminal region of human IRF-2.

Primary or Secondary

Primary

Content And Storage

-20°C, Avoid Freeze/Thaw Cycles

Gene

IRF2

Concentration

Lot-Specific

Classification

Polyclonal

Form

Liquid

Regulatory Status

RUO

Formulation

PBS with 30% glycerol and 0.035% sodium azide; pH 7.5

Gene Alias

9830146E22Rik; AI646973; DKFZp686F0244; Interferon regulatory factor 2; IRF2; IRF-2; OTTHUMP00000218576; OTTHUMP00000218580

Gene Symbols

IRF2

Isotype

IgG

Purification Method

Antigen affinity chromatography

Product Type

Antibody

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Description

  • IRF2 belongs to the interferon regulatory factor family
  • IRF2 regulates the transcription regulation important to cell proliferation as well as immune responses by binding to the upstream regulatory region of type I IFN and IFNinducible MHC class I genes (the interferon consensus sequence (ICS)) and repression of those genes
  • However, IRF2 also functions as a transcriptional activator of histone H4 by interactions with NF-kappa B.