Aiolos Monoclonal Antibody (8B2), Active Motif™
Mouse Monoclonal Antibody
Manufacturer: Fischer Scientific
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Antigen
Aiolos
Concentration
1 mg/mL
Classification
Monoclonal
Form
Liquid
Regulatory Status
RUO
Formulation
70mM tris with 0.07mM EDTA, 105mM NaCl, 30% glycerol, 31mM glycine and 0.035% sodium azide; pH 8
Gene Alias
5830411O07Rik; AIO; AIOLOS; BOS_19124; IKAROS family zinc finger 3; IKAROS family zinc finger 3 (Aiolos); Ikaros family zinc finger protein 3; Ikzf3; LOC100356392; Zfpn1a3; zinc finger DNA binding protein Aiolos; Zinc finger protein Aiolos; zinc finger protein, subfamily 1A, 3 (Aiolos); ZNFN1A3
Gene Symbols
Ikzf3
Isotype
IgG
Purification Method
Protein G
Product Type
Antibody
Clone
8B2
Applications
ChIP Assay, Western Blot
Conjugate
Unconjugated
Host Species
Mouse
Target Species
Mouse
Gene Accession No.
O08900
Gene ID (Entrez)
22780
Immunogen
This Aiolos antibody was raised against the N-terminal half of mouse Aiolos protein.
Primary or Secondary
Primary
Content And Storage
-20°C, Avoid Freeze/Thaw Cycles
Gene
Ikzf3
Related Products
Description
- This gene encodes a member of the Ikaros family of zinc-finger proteins
- Three members of this protein family (Ikaros, Aiolos and Helios) are hematopoietic-specific transcription factors involved in the regulation of lymphocyte development
- This gene product is a transcription factor that is important in the regulation of B lymphocyte proliferation and differentiation
- Both Ikaros and Aiolos can participate in chromatin remodeling
- Regulation of gene expression in B lymphocytes by Aiolos is complex as it appears to require the sequential formation of Ikaros homodimers, Ikaros/Aiolos heterodimers, and Aiolos homodimers
- At least six alternative transcripts encoding different isoforms have been described.