BRD2 Polyclonal Antibody, Active Motif™
Rabbit Polyclonal Antibody
Manufacturer: Fischer Scientific
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Antigen
BRD2
Applications
ChIP sequencing (ChIP-seq)
Conjugate
Unconjugated
Host Species
Rabbit
Target Species
Human
Gene Accession No.
P25440
Gene ID (Entrez)
6046
Immunogen
This BRD2 antibody was raised against a recombinant protein comprising amino acids 58-232 of human BRD2 (NP_005095 ).
Primary or Secondary
Primary
Content And Storage
-20°C, Avoid Freeze/Thaw Cycles
Gene
BRD2
Concentration
Lot-Specific
Classification
Polyclonal
Form
Liquid
Regulatory Status
RUO
Formulation
PBS with 30% glycerol and 0.035% sodium azide; pH 7.5
Gene Alias
AW228947; BRD2; bromodomain containing 2; bromodomain-containing 2; Bromodomain-containing protein 2; D17H6S113E; D6S113E; DADB-17J1.3; DKFZp686N0336; female sterile homeotic-related gene 1; Female sterile homeotic-related protein 1; FLJ31942; Frg-1; FSH; Fsrg1; Fsrg-1; Kiaa4005; KIAA9001; mKIAA4005; NAT; O27.1.1; Protein RING3; Really interesting new gene 3 protein; Ring3; RING3 protein; Rnf3
Gene Symbols
BRD2
Isotype
IgG
Purification Method
Antigen affinity chromatography
Product Type
Antibody
Related Products
Description
- This gene encodes a transcriptional regulator that belongs to the BET (bromodomains and extra terminal domain) family of proteins
- This protein associates with transcription complexes and with acetylated chromatin during mitosis, and it selectively binds to the acetylated lysine-12 residue of histone H4 via its two bromodomains
- The gene maps to the major histocompatibility complex (MHC) class II region on chromosome 6p21
- 3, but sequence comparison suggests that the protein is not involved in the immune response
- This gene has been implicated in juvenile myoclonic epilepsy, a common form of epilepsy that becomes apparent in adolescence
- Multiple alternatively spliced variants have been described for this gene, but the full-length nature of some of these variants has not been determined.