7188796

Histone H4K31me1 Polyclonal Antibody, Active Motif™

Rabbit Polyclonal Antibody

Manufacturer: Fischer Scientific

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Antigen

Histone H4K31me1

Applications

Dot Blot, Western Blot

Conjugate

Unconjugated

Host Species

Rabbit

Target Species

Human

Immunogen

This Histone H4 monomethyl Lys31 antibody was raised against a peptide containing monomethyl Lys31 of human histone H4.

Primary or Secondary

Primary

Product Type

Antibody

Concentration

Conc. Not Determined

Classification

Polyclonal

Form

Liquid

Regulatory Status

RUO

Formulation

whole serum with 30% glycerol and 0.035% sodium azide; pH

Isotype

IgG

Content And Storage

-20°C, Avoid Freeze/Thaw Cycles

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Description

  • Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes
  • Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes
  • The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures
  • This gene is intronless and encodes a member of the histone H4 family
  • Transcripts from this gene lack polyA tails but instead contain a palindromic termination element
  • This gene is found in the large histone gene cluster on chromosome 6.