7188813
Histone H4K8K12K16 (pan-biotinylated) Polyclonal Antibody, Biotin, Active Motif™
Rabbit Polyclonal Antibody
Manufacturer: Fischer Scientific
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Antigen
Histone H4K8K12K16 (pan-biotinylated)
Applications
Dot Blot
Conjugate
Biotin
Host Species
Rabbit
Target Species
Human
Immunogen
This antibody was raised against a synthetic peptide containing biotin-Lys 12 of human Histone H4.
Primary or Secondary
Primary
Product Type
Antibody
Concentration
Conc. Not Determined
Classification
Polyclonal
Form
Liquid
Regulatory Status
RUO
Formulation
whole serum with 30% glycerol and 0.035% sodium azide; pH
Isotype
IgG
Content And Storage
-20°C, Avoid Freeze/Thaw Cycles
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Description
- Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes
- Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes
- The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures
- This gene is intronless and encodes a member of the histone H4 family
- Transcripts from this gene lack polyA tails but instead contain a palindromic termination element
- This gene is found in the large histone gene cluster on chromosome 6.