7200646

Fc gamma RIIIA/CD16a Antibody (DJ130c) - BSA Free, Novus Biologicals™

Mouse Monoclonal Antibody

Manufacturer: Fischer Scientific

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Antigen

Fc gamma RIIIA/CD16a

Concentration

1.0 mg/mL

Applications

Immunohistochemistry (Frozen), Flow Cytometry, Immunohistochemistry, Immunohistochemistry (Paraffin)

Conjugate

Unconjugated

Host Species

Mouse

Target Species

Human

Gene Alias

CD16a, CD16a antigen, CD16FCRIIIA, Fc fragment of IgG, low affinity IIIa, receptor (CD16a), Fc fragment of IgG, low affinity IIIa, receptor for (CD16), Fc gamma receptor III-A, FCG3, Fc-gamma receptor III-2 (CD 16), Fc-gamma receptor IIIb (CD16), Fc-gamma RIII, Fc-gamma RIIIa, Fc-gamma RIII-alpha, FCGR3, FCGRIII, FCR-10, FcRIII, FcRIIIa, IGFR3FcgammaRIIIA, immunoglobulin G Fc receptor III, low affinity III, receptor for (CD16), low affinity immunoglobulin gamma Fc region receptor III-A, neutrophil-specific antigen NA

Gene Symbols

FCGR3A

Isotype

IgG1

Purification Method

Protein A or G purified

Test Specificity

NB100-64346 recognizes human CD16, a 50-65kD cell surface molecule, which is the low affinity receptor for IgG (FcR III). CD16 exists as a transmembranous form (Fc gammaRIIIA, or CD16A) and a glycosyl phosphatidylinositol (GPI) anchored form (Fc gammaRIIIB, or CD16B). CD16A is expressed by NK cells, some T cells, and macrophages, whereas CD16B is primarily expressed by granulocytes. In addition, CD16B exists as two allelic variants NA1 and NA2. DJ130c recognizes all polymorphonuclear cells irrespective on their NA phenotype. Studies show that the DJ130c antibody recognizes an epitope in the first membrane-distal domain of CD16 and recognizes both CD16A and CD16B.

Clone

DJ130c

Dilution

Flow Cytometry 1:10-1:1000, Immunohistochemistry 1:10-1:500, Immunohistochemistry-Paraffin 1:10-1:500, Immunohistochemistry-Frozen 1:10-1:500

Classification

Monoclonal

Form

Purified

Regulatory Status

RUO

Gene Accession No.

P08637

Gene ID (Entrez)

2214

Immunogen

CD34 antigen

Primary or Secondary

Primary

Content And Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

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Description

  • Fc gamma RIIIA/CD16a Monoclonal specifically detects Fc gamma RIIIA/CD16a in Human samples
  • It is validated for Flow Cytometry, Immunohistochemistry, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen.